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联合身体-认知训练对轻度认知障碍老年人的功能和认知能力的影响:一项随机对照试验。

Effect of combined physical-cognitive training on the functional and cognitive capacity of older people with mild cognitive impairment: a randomized controlled trial.

机构信息

Department of Health Sciences, Faculty of Health Sciences, University of Jaén, Jaén, 23071, Spain.

Department of Health Sciences, Faculty of Health Sciences, University of Atlántico Medio, Las Palmas de Gran Canaria, 35017, Spain.

出版信息

BMC Med. 2024 Jul 8;22(1):281. doi: 10.1186/s12916-024-03469-x.

Abstract

BACKGROUND

The increase in population aging highlights the growing prevalence of mild cognitive impairment, prompting the adoption of interventions that combine physical exercise and cognitive training to improve health and cognitive performance in older adults. The aim of this study was to analyze the efficacy of a combined program on physical and cognitive health in older people with cognitive impairment.

METHODS

A 12-week randomized controlled clinical trial involving 95 participants (aged 72.12 ± 4.25 years), 47 individuals participated in a control group (CG) that only underwent cognitive stimulation, while 48 individuals were in an experimental group (EG) that participated in a combined program. Balance was measured using the Tinetti scale, upper body strength was assessed with the arm curl test, lower body strength was evaluated with the 30-s chair stand test, flexibility was tested using the back scratch test and chair sit-and-reach test, physical function was measured with the Timed Up and Go test, cognitive function was assessed using the Mini Mental State Examination, cognitive impairment was evaluated with the Montreal Cognitive Assessment, verbal fluency was tested with the Isaac test, and executive functions were assessed using the Trail Making Test.

RESULTS

The results of the study show significant improvements in both physical and cognitive aspects, such as balance, gait, upper and lower body strength, flexibility, physical function, cognitive function, cognitive impairment, verbal fluency, and executive functions in the group that carried out the intervention compared to the control group.

CONCLUSION

A combined program for older individuals with mild cognitive impairment leads to enhancements in physical and cognitive health. These improvements underscore the importance of integrating physical exercise with cognitive training as an effective strategy for enhancing overall health and quality of life in older adults.

TRIAL REGISTRATION

NCT05503641.

摘要

背景

人口老龄化的增加凸显了轻度认知障碍患病率的上升,促使人们采用将体育锻炼和认知训练相结合的干预措施,以提高老年人的健康和认知能力。本研究旨在分析针对认知障碍老年人的联合干预方案对身体和认知健康的疗效。

方法

一项为期 12 周的随机对照临床试验,共纳入 95 名参与者(年龄 72.12±4.25 岁),其中 47 名参与者被分配至对照组(CG),仅接受认知刺激,而 48 名参与者被分配至实验组(EG),接受联合干预方案。使用 Tinetti 量表评估平衡,使用手臂卷曲测试评估上肢力量,使用 30 秒坐站测试评估下肢力量,使用背部抓挠测试和坐立前伸测试评估柔韧性,使用计时起立行走测试评估身体功能,使用简易精神状态检查评估认知功能,使用蒙特利尔认知评估评估认知障碍,使用 Isaac 测试评估言语流畅性,使用 Trail Making Test 评估执行功能。

结果

研究结果显示,与对照组相比,接受干预的组在平衡、步态、上肢和下肢力量、柔韧性、身体功能、认知功能、认知障碍、言语流畅性和执行功能等身体和认知方面均有显著改善。

结论

针对轻度认知障碍老年人的联合方案可改善身体和认知健康。这些改善强调了将体育锻炼与认知训练相结合作为提高老年人整体健康和生活质量的有效策略的重要性。

试验注册号

NCT05503641。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b198/11229192/7ceb78b26640/12916_2024_3469_Fig1_HTML.jpg

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