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一项对急性损伤老年患者衰弱评分和跌倒预测的前瞻性比较。

A Prospective Comparison of Frailty Scores and Fall Prediction in Acutely Injured Older Adults.

机构信息

Division of Burn Surgery, Department of Surgery, University of California, Davis, Sacramento, California.

School of Medicine, University of Michigan, Ann Arbor, Michigan.

出版信息

J Surg Res. 2021 Jan;257:326-332. doi: 10.1016/j.jss.2020.08.007. Epub 2020 Sep 2.

Abstract

BACKGROUND

Elderly (65 and older) fall-related injuries are a significant cause of morbidity and mortality. Although frailty predicts poor outcomes in geriatric trauma, literature comparing frailty scoring systems remains limited. Herein, we evaluated which frailty scoring system best predicts falls over time in the elderly.

MATERIALS AND METHODS

Acute surgical patients 65 y and older were enrolled and prospectively observed. Demographics and frailty, assessed using the FRAIL Scale, Trauma Specific Frailty Index (TSFI), and Canadian Frailty Scale (CSHA-CFS), were collected at enrollment and 3 mo intervals following discharge for 1 y. Surveys queried the total number and timing of falls. Changes in frailty over time were assessed by logistic regression and area under the curve (AUC).

RESULTS

Fifty-eight patients were enrolled. FRAIL Scale and CSHA-CFS scores did not change over time, but TSFI scores did (P ≤ 0.01). Worsening frailty was observed using TSFI at 6 (P ≤ 0.01) and 12 mo (P ≤ 0.01) relative to baseline. Mortality did not differ based on frailty using any frailty score. Increasing frailty scores and time postdischarge was associated with increased odds of a fall. AUC estimates with 95% CI were 0.72 [0.64, 0.80], 0.81 [0.74, 0.88], and 0.76 [0.68, 0.84] for the FRAIL Scale, TSFI, and CSHA-CFS, respectively.

CONCLUSIONS

The risk of falls postdischarge were associated with increased age, time postdischarge, and frailty in our population. No scale appeared to significantly outperform the other by AUC estimation. Further study on the longitudinal effects of frailty is warranted.

摘要

背景

老年人(65 岁及以上)与跌倒相关的伤害是发病率和死亡率的一个重要原因。尽管脆弱预测老年创伤的不良结局,但比较脆弱评分系统的文献仍然有限。在此,我们评估了哪种脆弱评分系统能最好地预测老年人随时间推移的跌倒。

材料和方法

纳入了 65 岁及以上的急性外科患者,并进行前瞻性观察。在入组时以及出院后 3 个月间隔收集了人口统计学和脆弱性数据,使用 FRAIL 量表、创伤特异性脆弱指数(TSFI)和加拿大脆弱性量表(CSHA-CFS)进行评估,随访时间为 1 年。调查询问了跌倒的总次数和时间。通过逻辑回归和曲线下面积(AUC)评估随时间变化的脆弱性变化。

结果

共纳入 58 例患者。FRAIL 量表和 CSHA-CFS 评分随时间无变化,但 TSFI 评分有变化(P≤0.01)。与基线相比,使用 TSFI 在 6 个月(P≤0.01)和 12 个月(P≤0.01)时观察到脆弱性恶化。使用任何脆弱性评分,死亡率均与脆弱性无关。出院后随时间推移,脆弱性评分增加与跌倒的几率增加相关。FRAIL 量表、TSFI 和 CSHA-CFS 的 AUC 估计值分别为 0.72[0.64, 0.80]、0.81[0.74, 0.88]和 0.76[0.68, 0.84]。

结论

在我们的人群中,出院后跌倒的风险与年龄增加、出院后时间和脆弱性有关。没有一个量表在 AUC 估计值方面明显优于其他量表。需要进一步研究脆弱性的纵向影响。

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本文引用的文献

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Frailty and Prognostication in Geriatric Surgery and Trauma.老年外科和创伤中的虚弱与预后。
Clin Geriatr Med. 2019 Feb;35(1):13-26. doi: 10.1016/j.cger.2018.08.002. Epub 2018 Oct 3.

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