Glaucoma Research Center, Montchoisi Clinic, Swiss Visio, Lausanne, Switzerland.
Viterbi Family Department of Ophthalmology, Shiley Eye Institute, Hamilton Glaucoma Center, University of California, San Diego, CA.
J Glaucoma. 2020 Nov;29(11):1030-1035. doi: 10.1097/IJG.0000000000001654.
To investigate the reliability of anterior chamber angle (ACA) measurements in narrow angles and assess the effect of laser peripheral iridotomy (LPI) on these measurements using novel swept-source optical coherence tomography (SS-OCT) technology.
In this prospective observational study, patients with gonioscopically narrow angles were enrolled and scheduled for prophylactic LPI. Twelve ACA sections were obtained in each eye using SS-OCT (ANTERION, Heidelberg Engineering, Germany) before and after Nd:YAG LPI. A built-in algorithm calculated ACA measurements after manual identification of the scleral spur and ACA recess. Eight ACA parameters were evaluated: ACA (ACA 500, ACA 750); scleral spur angle (SSA 500, SSA 750); angle opening distance (AOD 500, AOD 750); and trabecular iris space area (TISA 500, TISA 750). The effect of LPI was assessed for each parameter, both nasally and temporally.
Ten patients (18 eyes) were enrolled (mean age, 61.8±13.6 y; 60.0% female individuals). On average, the ACA was wider nasally than temporally (P=0.004). LPI significantly widened the ACA (range, 26.7-29.4%; P<0.05). ACA 500 increased by 29.4% (P<0.001), ACA 750 by 29.2% (P=0.002), SSA 500 by 27.3% (P=0.003), SSA 750 by 28.1% (P=0.001), AOD 500 by 28.6% (P=0.009), AOD 750 by 28.6% (P=0.003), TISA 500 by 27.3% (P=0.004), and TISA 750 by 26.7% (P=0.200).
SS-OCT ANTERION imaging can be used to reliably measure ACA before and after LPI. ACA, AOD, SSA, and TISA are all valid ACA measurement methods.
利用新型扫频源光学相干断层扫描（SS-OCT）技术，研究窄房角患者前房角（ACA）测量的可靠性，并评估激光周边虹膜切开术（LPI）对这些测量值的影响。
本前瞻性观察研究纳入了房角镜检查显示窄角的患者，并计划进行预防性 LPI。使用 SS-OCT（德国海德堡工程公司的 ANTERION）在 Nd：YAG LPI 前后分别获得每只眼的 12 个 ACA 节段。内置算法在手动识别巩膜突和 ACA 隐窝后计算 ACA 测量值。评估了 8 个 ACA 参数：ACA（ACA 500、ACA 750）；巩膜突角（SSA 500、SSA 750）；房角开放距离（AOD 500、AOD 750）；小梁虹膜空间面积（TISA 500、TISA 750）。评估了 LPI 对每个参数的影响，包括鼻侧和颞侧。
共纳入 10 名患者（18 只眼）（平均年龄 61.8±13.6 岁；60.0%为女性）。平均而言，ACA 鼻侧比颞侧更宽（P=0.004）。LPI 显著扩大了 ACA（范围 26.7%-29.4%；P<0.05）。ACA 500 增加了 29.4%（P<0.001），ACA 750 增加了 29.2%（P=0.002），SSA 500 增加了 27.3%（P=0.003），SSA 750 增加了 28.1%（P=0.001），AOD 500 增加了 28.6%（P=0.009），AOD 750 增加了 28.6%（P=0.003），TISA 500 增加了 27.3%（P=0.004），TISA 750 增加了 26.7%（P=0.200）。
SS-OCT ANTERION 成像可用于可靠测量 LPI 前后的 ACA。ACA、AOD、SSA 和 TISA 都是有效的 ACA 测量方法。
