Chen Shi-Yan, He Na, Yan Yu-Jie, Fan Xiang, Wu Ling-Ling
Department of Ophthalmology, Peking University Third Hospital, Peking University Eye Centre, Beijing 100191, China.
Department of Ophthalmology, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Chengdu 610072, Sichuan Province, China.
Int J Ophthalmol. 2022 Sep 18;15(9):1476-1482. doi: 10.18240/ijo.2022.09.10. eCollection 2022.
To compare the ciliary body thickness between eyes with primary angle closure (PAC) and primary angle-closure glaucoma (PACG) with the normal eyes, and to investigate the association between ciliary body thickness and ciliary processes situation.
In this cross-sectional study, 57 patients with PAC/PACG were matched to 57 normal subjects after propensity score matching (PSM) adjusting for age and gender. All subjects underwent conventional ocular examinations and ultrasound biomicroscopy (UBM) examination, among which the patients with PAC/PACG performed the examinations one month after laser peripheral iridotomy (LPI). Quantitative parameters were measured, which included ciliary body thickness at the position of 1 mm posterior to the scleral spur (CBT1), trabecular-ciliary process distance (TCPD) and trabecular-ciliary process angle (TCA).
Eyes with PAC/PACG presented significantly thinner CBT1, shorter TCPD and smaller TCA (<0.001) than the normal eyes, both in comparison of the means of four quadrants and in comparisons of each quadrant. After removing images with peripheral anterior synechia (PAS), the same results were also found in comparisons between the two groups. Significant correlations were found between TCPD ( =0.537, <0.001) and TCA ( =0.517, <0.001) with CBT1.
Eyes with PAC/PACG have thinner ciliary body thickness and more anteriorly situated ciliary processes. Thinner ciliary body thickness is associated with anterior situation of the ciliary processes.
比较原发性房角关闭（PAC）和原发性闭角型青光眼（PACG）患眼与正常眼的睫状体厚度，并探讨睫状体厚度与睫状突情况之间的关联。
在这项横断面研究中，对57例PAC/PACG患者进行倾向得分匹配（PSM）以调整年龄和性别后，与57名正常受试者进行匹配。所有受试者均接受常规眼科检查和超声生物显微镜（UBM）检查，其中PAC/PACG患者在激光周边虹膜切开术（LPI）后1个月进行检查。测量定量参数，包括巩膜突后1mm处的睫状体厚度（CBT1）、小梁-睫状突距离（TCPD）和小梁-睫状突夹角（TCA）。
无论是比较四个象限的均值还是每个象限的比较，PAC/PACG患眼的CBT1均显著薄于正常眼，TCPD显著短于正常眼，TCA显著小于正常眼（<0.001）。去除周边前粘连（PAS）图像后，两组之间的比较也得到相同结果。发现TCPD（=0.537，<0.001）和TCA（=0.517，<0.001）与CBT1之间存在显著相关性。
PAC/PACG患眼的睫状体厚度更薄，睫状突位置更靠前。睫状体厚度变薄与睫状突靠前有关。
