Kim's Eye Hospital, Seoul, Korea.
Department of Ophthalmology, Institute of Vision Research, Yonsei University College of Medicine, Seoul, South Korea.
PLoS One. 2022 Nov 21;17(11):e0277703. doi: 10.1371/journal.pone.0277703. eCollection 2022.
To measure angle-to-angle (ATA) and spur-to-spur (STS) distances along six meridians using swept-source optical coherence tomography (SS-OCT) and compare with horizontal white-to-white (WTW) distance in different refractive error.
Overall, 126 eyes were assessed with the Anterion SS-OCT (Heidelberg Engineering, Heidelberg, Germany). ATA and STS distances were obtained using SS-OCT at 0, 30, 60, 90, 120, and 150 degrees. WTW was measured at 0 degree with built-in infrared camera. One way ANOVA test, pearson correlation coefficient, and stepwise multivariate regression analysis were used to compare ATA and STS distances with age, anterior chamber depth (ACD), axial length (AL), and simulated keratometric values (Sim K) in different refractive error groups.
The mean MRSE refraction was +0.05 ± 0.23 D in the emmetropic group (41 eyes), -3.42 ± 3.04 D in the myopic group (44 eyes), and +1.33 ± 0.64 D in the hyperopic group (31 eyes). There was no statistical difference in the WTW of the emmetropic (11.62 ± 0.44 mm), myopic (11.79 ± 0.46 mm), and hyperopic groups (11.80 ± 0.49 mm) using one-way ANOVA (p = 0.007). ATA and STS were vertically oval in all groups. The correlation between ATA, STS and age, ACD, AL, and K values showed different significance for each meridian according to the refractive error. ATA increased as the horizontal WTW, ACD, and AL increased and Sim K decreased. STS shows relatively smaller explanatory power than ATA in the stepwise multivariate regression analysis.
This study is the first to analyze the relationship between ATA and STS compared to WTW by different refractive error. The difference between the horizontally oval WTW and vertically oval anterior chamber can be large, especially in myopia. ATA showed a greater positive correlation than STS with AL and ACD.
使用扫频源光学相干断层扫描（SS-OCT）测量 6 条子午线上的角对角（ATA）和齿对齿（STS）距离，并比较不同屈光不正的水平白对白（WTW）距离。
共评估 126 只眼，使用 Anterion SS-OCT（德国海德堡工程公司）。使用 SS-OCT 在 0、30、60、90、120 和 150 度获得 ATA 和 STS 距离。内置红外摄像头在 0 度测量 WTW。采用单因素方差分析、皮尔逊相关系数和逐步多元回归分析比较不同屈光不正组中 ATA 和 STS 距离与年龄、前房深度（ACD）、眼轴长度（AL）和模拟角膜曲率值（Sim K）的关系。
在正视组（41 只眼）中，平均等效球镜（MRSE）屈光度为+0.05 ± 0.23 D，在近视组（44 只眼）中为-3.42 ± 3.04 D，在远视组（31 只眼）中为+1.33 ± 0.64 D。在正视（11.62 ± 0.44 mm）、近视（11.79 ± 0.46 mm）和远视（11.80 ± 0.49 mm）组中，WTW 无统计学差异（单因素方差分析，p = 0.007）。在所有组中，ATA 和 STS 均呈垂直椭圆形。根据屈光不正，ATA、STS 与年龄、ACD、AL 和 K 值之间的相关性在每个子午线都有不同的意义。ATA 随水平 WTW、ACD 和 AL 增加以及 Sim K 降低而增加。在逐步多元回归分析中，STS 的解释力相对小于 ATA。
本研究首次分析了不同屈光不正时 ATA 和 STS 与 WTW 的关系。水平椭圆形 WTW 和垂直椭圆形前房之间的差异可能很大，尤其是在近视中。ATA 与 AL 和 ACD 的相关性大于 STS。
