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Ivermectin may be a clinically useful anti-inflammatory agent for late-stage COVID-19.

作者信息

DiNicolantonio James J, Barroso Jorge, McCarty Mark

机构信息

Department of Preventive Cardiology, Mid America Heart Insitute, Kansas, Missouri, USA

Clinica Libre de Adicciones, Tijuana, Baja California, Mexico.

出版信息

Open Heart. 2020 Sep;7(2). doi: 10.1136/openhrt-2020-001350.

DOI:10.1136/openhrt-2020-001350
PMID:32895293
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7476419/
Abstract
摘要

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Use of Ivermectin Is Associated With Lower Mortality in Hospitalized Patients With Coronavirus Disease 2019: The Ivermectin in COVID Nineteen Study.使用伊维菌素与 COVID-19 住院患者的死亡率降低相关:COVID-19 中的伊维菌素研究。
Chest. 2021 Jan;159(1):85-92. doi: 10.1016/j.chest.2020.10.009. Epub 2020 Oct 13.
2
Extracellular HMGB1: a therapeutic target in severe pulmonary inflammation including COVID-19?细胞外 HMGB1:严重肺部炎症(包括 COVID-19)的治疗靶点?
Mol Med. 2020 May 7;26(1):42. doi: 10.1186/s10020-020-00172-4.
3
The Approved Dose of Ivermectin Alone is not the Ideal Dose for the Treatment of COVID-19.伊维菌素单独批准的剂量不是治疗 COVID-19 的理想剂量。
Clin Pharmacol Ther. 2020 Oct;108(4):762-765. doi: 10.1002/cpt.1889. Epub 2020 Jun 7.
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Antiviral Res. 2020 Jun;178:104787. doi: 10.1016/j.antiviral.2020.104787. Epub 2020 Apr 3.
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Topical ivermectin improves allergic skin inflammation.局部使用伊维菌素可改善过敏性皮肤炎症。
Allergy. 2017 Aug;72(8):1212-1221. doi: 10.1111/all.13118. Epub 2017 Feb 6.
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Anti-inflammatory effects of ivermectin in mouse model of allergic asthma.伊维菌素对过敏性哮喘小鼠模型的抗炎作用。
Inflamm Res. 2011 Jun;60(6):589-96. doi: 10.1007/s00011-011-0307-8. Epub 2011 Jan 29.
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Phylogeny and metabolic scaling in mammals.哺乳动物的系统发育和代谢缩放。
Ecology. 2010 Sep;91(9):2783-93. doi: 10.1890/09-0817.1.
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Fundam Clin Pharmacol. 2009 Aug;23(4):449-55. doi: 10.1111/j.1472-8206.2009.00684.x. Epub 2009 May 6.
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Int Immunopharmacol. 2009 Mar;9(3):354-9. doi: 10.1016/j.intimp.2008.12.016. Epub 2009 Jan 23.
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Inflamm Res. 2008 Nov;57(11):524-9. doi: 10.1007/s00011-008-8007-8.