Ramon y Cajal University Hospital.
European University of Madrid.
Acta Reumatol Port. 2020 Apr-Jun;45(2):104-110.
Ultrasound study of the wrist in patients with suspected entrapment syndrome has severe limitations due to the variability of what is considered normal for the cross-sectional area of the median nerve and where to proceed to measure it. We aim to determine the extent to which different anthropometric variables influence the median nerve area in subjects without carpal tunnel syndrome.
We conducted an observational study based on a multivariate linear regression analysis using as a dependent variable the area of the median nerve cut at two specific points in the wrist of healthy subjects. The independent variables were sex, age, height, weight, body mass index, finger flexor strength, and carpal circumference.
The measurements of the median nerve cross-sectional area were normalized using a quadratic fixing procedure. Of all the variables included in the linear regression analysis, only carpal circumference and sex (0: female, 1: male) contributed significantly in the final model using the wrist crease as the measurement point (Constant B=-209.45, carpal circumference coefficient=21.07, sex coefficient 10.87). At four centimeters distal to the carpal fold, the model included the same variables (Constant B=-221.84, carpal circumference coefficient=24.01, and sex coefficient=11.41).
Both the wrist circumference and the sex are variables that should be considered to determine cut-off points of normality in future validation studies about the cross-sectional area of the median nerve.
由于正中神经横截面积的正常值存在差异，并且测量位置也不明确，因此对手腕疑似卡压综合征患者进行超声检查存在严重局限性。我们旨在确定不同人体测量学变量在没有腕管综合征的受试者中对正中神经区域的影响程度。
我们进行了一项基于多元线性回归分析的观察性研究，将健康受试者腕部两个特定部位正中神经截面积作为因变量。自变量为性别、年龄、身高、体重、体重指数、指屈肌力量和腕周径。
使用二次固定程序对正中神经横截面积的测量值进行了归一化。在线性回归分析中包含的所有变量中，只有腕周径和性别（0：女性，1：男性）在以腕褶为测量点的最终模型中具有显著贡献（常数 B=-209.45，腕周径系数=21.07，性别系数 10.87）。在腕褶 4 厘米远的位置，模型包含相同的变量（常数 B=-221.84，腕周径系数=24.01，性别系数=11.41）。
腕周径和性别均为应考虑的变量，以便在未来关于正中神经横截面积的正常值验证研究中确定截断值。
