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法匹拉韦:COVID-19 中一种新兴的抗病毒新选择。

Favipiravir: A new and emerging antiviral option in COVID-19.

作者信息

Agrawal Umang, Raju Reyma, Udwadia Zarir F

机构信息

Associate Consultant (Infectious Diseases), PD Hinduja National Hospital and Medical Research Centre, Mumbai, India.

Clinical Assistant (Pulmonary Medicine), PD Hinduja National Hospital and Medical Research Centre, Mumbai, India.

出版信息

Med J Armed Forces India. 2020 Oct;76(4):370-376. doi: 10.1016/j.mjafi.2020.08.004. Epub 2020 Sep 2.

Abstract

With over 16 million cases reported from across the globe, the SARS-CoV-2, a mere 125 microns in diameter, has left an indelible impact on our world. With the paucity of new drugs to combat this disease, the medical community is in a race to identify repurposed drugs that may be effective against this novel coronavirus. One of the drugs which has recently garnered much attention, especially in India, is an anti-viral drug originally designed for influenza, called favipiravir. In this article, we have tried to provide a comprehensive, evidence-based review of this drug in the context of the present pandemic to elucidate its role in the management of COVID-19.

摘要

全球报告的病例超过1600万例,直径仅125微米的严重急性呼吸综合征冠状病毒2(SARS-CoV-2)给我们的世界留下了不可磨灭的影响。由于对抗这种疾病的新药匮乏,医学界正在竞相寻找可能对这种新型冠状病毒有效的 repurposed 药物。最近备受关注的一种药物,尤其是在印度,是一种最初设计用于治疗流感的抗病毒药物,名为法匹拉韦。在本文中,我们试图在当前大流行的背景下对这种药物进行全面的、基于证据的综述,以阐明其在2019冠状病毒病管理中的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/838d/7606086/73528b9f1b39/gr1.jpg

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