Department of Pharmacy Practice, JSS College of Pharmacy, JSSAHER Mysuru, Karnataka, India.
J Infect Dev Ctries. 2020 Aug 31;14(8):929-930. doi: 10.3855/jidc.12148.
Approximately 2-3% of hospitalized patients are known to experience an adverse drug reaction (ADR). Dermatologic ADRs account for 10-30% of ADRs, and are commonly reported to be associated with antibiotic use. The classes of antibiotics most commonly reported to cause cutaneous reactions are the penicillins, cephalosporins, and fluoroquinolones. Polymyxin E is known to cause such reactions, but rarely. Here, we report a case of a colistin- induced maculopapular rash in an 84-year-old male. To the best of our knowledge, this is the first case of colistin-induced maculopapular rash to be reported in India.
据报道，约有 2-3%的住院患者会发生药物不良反应（ADR）。皮肤药物不良反应占 ADR 的 10-30%，通常与抗生素的使用有关。最常报告引起皮肤反应的抗生素类别是青霉素类、头孢菌素类和氟喹诺酮类。黏菌素 E 已知会引起此类反应，但很少见。在这里，我们报告了一例 84 岁男性因多粘菌素 E 引起的斑丘疹。据我们所知，这是印度首例多粘菌素 E 引起的斑丘疹病例。
