Matossian Cynthia
Matossian Eye Associates, Pennington, NJ, USA.
Clin Ophthalmol. 2020 Aug 12;14:2283-2289. doi: 10.2147/OPTH.S263046. eCollection 2020.
This study aimed to assess the effects of thermal pulsation system (TPS) treatment on astigmatism management in meibomian gland dysfunction (MGD) patients undergoing cataract surgery.
This single-center pilot study included 25 eyes of 23 patients who had visually significant cataract and concomitant MGD-associated dry eye in at least 1 eye and were willing to undergo TPS treatment and wait for at least 6 weeks for tear film stabilization prior to cataract surgery. Post-TPS keratometric readings were used for presurgical planning, and the actual postoperative residual refractive astigmatism (RRA) was recorded. Pre-TPS keratometry was used to mathematically simulate the RRA that would have been obtained from the lens choice and astigmatism management without TPS treatment.
Following TPS treatment, the magnitude of astigmatism increased in 52% of eyes, decreased in 24%, and remained unchanged in 24%. Correspondingly, astigmatism treatment modality changed in 68% of eyes after tear film stabilization with TPS treatment. The type of astigmatism management increased (ie, shifted from no treatment to LRI or LRI to toric IOL) in 25% of eyes and decreased in 8%. Actual RRA ≤0.5 D was achieved in 76% of eyes, compared to simulated RRA ≤0.5 D in 40% of eyes (=0.004).
Stabilization of the tear film with TPS treatment resulted in less RRA than if pre-TPS keratometric readings had been used to determine the astigmatism management method and toric IOL power and axis.
本研究旨在评估热脉动系统(TPS)治疗对白内障手术患者睑板腺功能障碍(MGD)散光管理的效果。
这项单中心前瞻性研究纳入了23例患者的25只眼,这些患者患有具有视觉显著性的白内障,且至少一只眼伴有MGD相关干眼,愿意接受TPS治疗,并在白内障手术前等待至少6周以使泪膜稳定。TPS治疗后的角膜曲率读数用于术前规划,并记录实际术后残余屈光性散光(RRA)。术前角膜曲率测量用于数学模拟在不进行TPS治疗的情况下,通过晶状体选择和散光管理所获得的RRA。
TPS治疗后,52%的眼睛散光度数增加,24%的眼睛散光度数降低,24%的眼睛散光度数保持不变。相应地,在TPS治疗使泪膜稳定后,68%的眼睛散光治疗方式发生了变化。25%的眼睛散光管理类型增加(即从无治疗转变为激光周边虹膜成形术[LRI]或从LRI转变为散光人工晶状体[IOL]),8%的眼睛散光管理类型减少。76%的眼睛实际RRA≤0.5 D,相比之下,模拟RRA≤0.5 D的眼睛为40%(P = 0.004)。
与使用TPS治疗前的角膜曲率读数来确定散光管理方法、散光IOL的度数和轴位相比,TPS治疗使泪膜稳定后导致的RRA更小。