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印度东部绵羊和山羊中绵羊小反刍兽疫的血清流行率

Seroprevalence of peste des petits ruminants in sheep and goats in Eastern India.

作者信息

Balamurugan V, Varghese Bibitha, Muthuchelvan D, Kumar K Vinod, Govindaraj G, Suresh K P, Kumar Pankaj, Hemadri D, Roy Parimal

机构信息

Indian Council of Agricultural Research -National Institute of Veterinary Epidemiology and Disease Informatics (ICAR-NIVEDI), Post Box No. 6450, Yelahanka, Bengaluru, Karnataka 560064 India.

Division of Virology, ICAR-Indian Veterinary Research Institute, Campus Mukteswar, Nainital, Uttarakhand 263138 India.

出版信息

Virusdisease. 2020 Sep;31(3):383-387. doi: 10.1007/s13337-020-00574-2. Epub 2020 Apr 8.

Abstract

The seroprevalence study of peste des petits ruminants (PPR) in small ruminants in Bihar and Odisha states in the Eastern region of India was carried out. A total of 1836 serum samples were collected from sheep (n = 648) and goats (n = 1188) from various epidemiological units (n = 112) in these states by a two-stage sampling plan during April 2017-March 2018. These samples were tested for the detection of virus antibodies by PPR competitive ELISA kit. The results revealed that the seroprevalence of PPR in sheep and goats in Bihar and Odisha states was 30.91% and 54.20%, respectively. Further, the chi-square analysis showed that the association exists between the presence of PPR virus antibodies in the goats (χ = 93.28,  < 0.01) and between the states (χ = 82.61,  < 0.01). This cross-sectional serosurvey also infers that the sheep and goats in most of the epi-units (n = 87) had < 70% of PPR virus antibodies prevalence. This warrants the intensive continuous mass vaccination program for a few more years to achieve the desired level of population immunity (epidemiological units protection level) and active surveillance to make these states free from PPR in the Eastern region of India.

摘要

在印度东部比哈尔邦和奥里萨邦对小反刍兽疫(PPR)进行了小反刍动物血清流行率研究。在2017年4月至2018年3月期间,通过两阶段抽样计划,从这些邦的各个流行病学单位(n = 112)的绵羊(n = 648)和山羊(n = 1188)中总共采集了1836份血清样本。使用PPR竞争ELISA试剂盒对这些样本进行病毒抗体检测。结果显示,比哈尔邦和奥里萨邦绵羊和山羊的PPR血清流行率分别为30.91%和54.20%。此外,卡方分析表明,山羊中PPR病毒抗体的存在之间存在关联(χ = 93.28,P < 0.01)以及邦之间存在关联(χ = 82.61,P < 0.01)。这项横断面血清学调查还推断,大多数流行病学单位(n = 87)的绵羊和山羊中PPR病毒抗体流行率< 70%。这就需要再持续开展几年强化大规模疫苗接种计划,以达到期望的群体免疫水平(流行病学单位保护水平),并进行主动监测,使印度东部这些邦摆脱PPR。

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