Acharya Narayan, Poudel Shankar Prasad, Acharya Krishna Prasad
1Texas Tech University, Lubbock, TX USA.
Institute of Agriculture and Animal Science (IAAS), Rampur, Chitwan, Nepal.
Virusdisease. 2018 Jun;29(2):173-179. doi: 10.1007/s13337-018-0449-1. Epub 2018 Apr 6.
A cross-sectional study was conducted to determine sero-prevalence of Peste des Petits Ruminants (PPR) among goat population of outbreak suspected areas; Kaski and Syangja districts of Nepal. A total of 460 goat serum samples were tested by using c-ELISA for the presence of antibodies against PPR. Out of the 460 samples tested, 380 samples were found positive, giving overall sero-positivity of 82.60%. Significantly higher sero-prevalence was found (< 0.05) in females (87.50%) compared to males (70.45%) and crossbreed goats were found highly susceptible than the pure breed goats (< 0.05). Likewise, higher sero-prevalence of PPR was observed in adults and cross breed goats compared to their counterparts and significantly higher sero-prevalence was observed in Syangja district compared to Kaski. Thus, adults, females and cross-breeds populations of goats are at higher risk of PPR whereas geographically, goat population of Syangja district were found significantly prone to PPR. Appropriate control measures, such as ring vaccination can be followed to prevent the potential outbreak situation.
开展了一项横断面研究，以确定尼泊尔卡斯凯和桑贾县疑似疫情地区山羊群体中小反刍兽疫（PPR）的血清流行率。使用c-ELISA对总共460份山羊血清样本进行检测，以确定是否存在抗PPR抗体。在检测的460份样本中，发现380份样本呈阳性，总体血清阳性率为82.60%。与雄性山羊（70.45%）相比，雌性山羊（87.50%）的血清流行率显著更高（<0.05），并且杂交山羊比纯种山羊更易感染（<0.05）。同样，与成年山羊和杂交山羊的对应群体相比，成年山羊和杂交山羊的PPR血清流行率更高，与卡斯凯县相比，桑贾县的血清流行率显著更高。因此，成年山羊、雌性山羊和杂交山羊群体感染PPR的风险更高，而从地理区域来看，发现桑贾县的山羊群体明显更容易感染PPR。可以采取适当的控制措施，如环状疫苗接种，以预防潜在的疫情爆发情况。
