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Leveraging Veterans Health Administration Clinical and Research Resources to Accelerate Discovery and Testing in Precision Oncology.利用退伍军人健康管理局的临床和研究资源，加速精准肿瘤学的发现与测试。
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2
The Precision Oncology Program for Cancer of the Prostate (POPCaP) Network: A Veterans Affairs/Prostate Cancer Foundation Collaboration.前列腺癌精准肿瘤学项目（POPCaP）网络：退伍军人事务部/前列腺癌基金会合作项目
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Evolving Intersection Between Inherited Cancer Genetics and Therapeutic Clinical Trials in Prostate Cancer: A White Paper From the Germline Genetics Working Group of the Prostate Cancer Clinical Trials Consortium.遗传性前列腺癌遗传学与治疗性临床试验之间不断演变的交叉点：来自前列腺癌临床试验联盟种系遗传学工作组的白皮书
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Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer.转移性前列腺癌的基因组特征和结构变异。
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The long tail of oncogenic drivers in prostate cancer.前列腺癌中致癌驱动基因的长尾现象。
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前列腺癌基金会与退伍军人事务部合作项目：公私合作推进侵袭性癌症治疗与护理的典范。

Prostate Cancer Foundation-Department of Veterans Affairs Partnership: A Model of Public-Private Collaboration to Advance Treatment and Care of Invasive Cancers.

作者信息

Levine Rebecca D, Ekanayake Ruwanthi N, Martin Ashley C, Dickson Kyle, McGarrell Kayla, Miyahira Andrea, Campbell Rebecca S, Johnson Thomas, Soule Howard R, Simons Jonathan W

机构信息

is Vice President, Government Affairs and National Director of the Veterans Health Initiative; is a Consultant; is Program Assistant, Government Affairs; and are Research Assistants, Government Affairs; is Executive Vice President, Chief Science Officer; is Director, Global Research and Scientific Communications; is Manager of Medical Content; is Assistant Chief of Staff; and is President and Chief Executive Officer; all at the Prostate Cancer Foundation.

出版信息

Fed Pract. 2020 Aug;37(Suppl 4):S32-S37. doi: 10.12788/fp.0035.

DOI:10.12788/fp.0035
PMID:32908352
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7473725/
Abstract

BACKGROUND

Prostate cancer is the most frequently diagnosed and treated cancer in the US Department of Veterans Affairs (VA). As the leading philanthropic source for prostate cancer research, the Prostate Cancer Foundation (PCF) entered into a unique public-private biomedical research partnership with the VA with the goal of addressing the urgent health challenges faced by veterans with prostate cancer.

OBSERVATIONS

With a commitment of $50 million from PCF and the VA's vast medical center infrastructure, the PCF-VA partnership has established 12 precision oncology Centers of Excellence to date, forming a collaborative network called the Precision Oncology Program for Cancer of the Prostate (POPCaP) Network. A 4-year review reveals the importance of executive leadership, mission-driven advocacy, setting shared ambitious goals, maximizing existing infrastructure and human capital, recruiting talent and resources, and creating space for adaptation and iteration in the context of a learning health care system.

CONCLUSIONS

The PCF-VA partnership seeks to continue translating clinical research into national standards of care for veterans and serves as an innovative model of public-private collaborations for future health initiatives.

摘要

背景

前列腺癌是美国退伍军人事务部（VA）诊断和治疗最为频繁的癌症。作为前列腺癌研究的主要慈善资金来源，前列腺癌基金会（PCF）与退伍军人事务部建立了独特的公私合营生物医学研究伙伴关系，旨在应对前列腺癌退伍军人面临的紧迫健康挑战。

观察结果

凭借前列腺癌基金会5000万美元的资金投入以及退伍军人事务部庞大的医疗中心基础设施，前列腺癌基金会与退伍军人事务部的伙伴关系迄今已建立了12个精准肿瘤卓越中心，形成了一个名为前列腺癌精准肿瘤项目（POPCaP）网络的协作网络。一项为期4年的评估揭示了行政领导、使命驱动的宣传、设定共同的宏伟目标、最大限度利用现有基础设施和人力资本、招募人才与资源，以及在学习型医疗系统背景下为适应和迭代创造空间的重要性。

结论

前列腺癌基金会与退伍军人事务部的伙伴关系力求继续将临床研究转化为退伍军人的全国护理标准，并成为未来健康倡议公私合作的创新模式。