Montgomery Bruce, Rettig Matthew, Kasten Jesse, Muralidhar Sumitra, Myrie Kenute, Ramoni Rachel
is an Oncologist and is Network Director at VA Puget Sound Health Care System in Seattle, Washington. is an Oncologist at the Greater Los Angeles Health Care System and a Professor of Medicine at the University of California, Los Angeles. is Program Director, Million Veteran Program. is Scientific Program Manager of Oncology and is Chief Research and Development Officer, all in the Office of Research and Development, Veterans Health Administration. Bruce Montgomery is a Professor of Medicine at the University of Washington in Seattle.
Fed Pract. 2020 Aug;37(Suppl 4):S48-S53. doi: 10.12788/fp.0021.
The promise of precision oncology only can be realized when genetic alterations are identified that can be lever-aged to improve response and minimize toxicity. Identifying those alterations as efficiently as possible and then giving patients access to targeted therapy and clinical study requires a comprehensive strategy across health care systems.
The US Department of Veterans Affairs (VA) and Prostate Cancer Foundation have established a network of VA centers to help develop best practices for precision oncology for the treatment of veterans with advanced prostate cancer. This article describes the genesis and structure of this network and its potential for contributing to care and research in the VA and the health care system as a whole.
The Precision Oncology Program for Cancer of the Prostate network and its partnership with VA clinical and research efforts is anticipated to provide important insights into barriers and solutions to the implementation of precision oncology for prostate cancer across the VA.
只有当识别出可用于改善反应并将毒性降至最低的基因改变时，精准肿瘤学的前景才能实现。尽可能高效地识别这些改变，然后让患者能够获得靶向治疗和参与临床研究，这需要整个医疗保健系统采取全面的策略。
美国退伍军人事务部（VA）和前列腺癌基金会已经建立了一个VA中心网络，以帮助制定针对晚期前列腺癌退伍军人的精准肿瘤学最佳实践。本文描述了该网络的起源、结构及其对VA以及整个医疗保健系统的护理和研究做出贡献的潜力。
前列腺癌精准肿瘤学项目网络及其与VA临床和研究工作的合作，有望为VA系统中前列腺癌精准肿瘤学实施的障碍和解决方案提供重要见解。
