来自酿酒酵母的一段189个核苷酸的可 dispensible（此处可能有误，推测为“可缺失的”，dispensable）小核仁RNA的序列及遗传分析
Sequence and genetic analysis of a dispensible 189 nucleotide snRNA from Saccharomyces cerevisiae.
作者信息
Thompson J R, Zagorski J, Woolford J L, Fournier M J
机构信息
Department of Biochemistry, University of Massachusetts, Amherst 01003.
出版信息
Nucleic Acids Res. 1988 Jun 24;16(12):5587-601. doi: 10.1093/nar/16.12.5587.
The structure of a Saccharomyces cerevisiae gene that encodes a small nuclear RNA (snRNA) of 189 nucleotides is described. This gene, designated SNR189, is located 400 base pairs upstream of the CRY1 gene on yeast chromosome III. Gene replacement analysis revealed the SNR189 gene to be dispensable for growth under a variety of culture conditions. The snR189 sequence lacks homology with other sequenced yeast or metazoan snRNAs.
本文描述了酿酒酵母中一个编码189个核苷酸的小核RNA（snRNA）的基因结构。这个名为SNR189的基因位于酵母III号染色体上CRY1基因上游400个碱基对处。基因置换分析表明，在多种培养条件下，SNR189基因对于细胞生长并非必需。snR189序列与其他已测序的酵母或后生动物snRNA没有同源性。
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