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老年人中的冠状病毒:英国迟封锁队列研究。

Coronavirus in the elderly: a late lockdown UK cohort.

机构信息

North West Anglia NHS Foundation Trust.

North West Anglia NHS Foundation Trust

出版信息

Clin Med (Lond). 2020 Nov;20(6):e222-e228. doi: 10.7861/clinmed.2020-0423. Epub 2020 Sep 10.

Abstract

OBJECTIVE

To identify the source of ongoing coronavirus disease 2019 (COVID-19) infections after 4 weeks of lockdown and to characterise the presentation of COVID-19 in the elderly, who represent the highest risk group.

DESIGN

Retrospective observational cohort study of 115 patients at one acute district general hospital with a catchment population of approximately 500,000 people, during weeks 5 and 6 of the UK lockdown.

RESULTS

More than 2 in 3 of the overall cohort had had contacts with the health and social care system prior to diagnosis. This figure rose to 85% in those 70 years and over. In the older cohort, the most common reasons for presentation were shortness of breath or falls, and 1 in 3 had neither cough nor fever.

CONCLUSION

COVID-19 can present differently in the elderly, overlapping with many common presentations, so focusing testing on those with a cough or fever will miss at least 1 in 3 cases in those over the age of 70. A high degree of vigilance, suspicion and repeated testing is required if streaming into high and low risk areas is to succeed, allowing safe restarting of services such as elective surgery and cancer care.

摘要

目的

在封锁 4 周后确定持续发生的 2019 年冠状病毒病(COVID-19)感染源,并描述代表最高风险群体的老年人中 COVID-19 的表现。

设计

对英国封锁的第 5 和第 6 周期间,一家拥有约 500,000 名居民的急性地区综合医院的 115 名患者进行回顾性观察性队列研究。

结果

总体队列中超过 2/3 的人在诊断前与卫生和社会保健系统有过接触。这一数字在 70 岁及以上的人群中上升到 85%。在老年人群中,最常见的就诊原因是呼吸急促或跌倒,三分之一的人既没有咳嗽也没有发烧。

结论

COVID-19 在老年人中的表现可能不同,与许多常见表现重叠,因此如果要将检测集中在有咳嗽或发烧的人群上,那么在 70 岁以上的人群中至少会漏诊三分之一的病例。如果要成功地将患者分为高风险和低风险区,需要高度警惕、怀疑和反复检测,从而可以安全地重启诸如选择性手术和癌症治疗等服务。

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Coronavirus in the elderly: a late lockdown UK cohort.老年人中的冠状病毒:英国迟封锁队列研究。
Clin Med (Lond). 2020 Nov;20(6):e222-e228. doi: 10.7861/clinmed.2020-0423. Epub 2020 Sep 10.

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