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老年髋部骨折手术患者无心力衰竭但术前存在心脏危险因素与院内死亡率的相关性:单中心研究。

Preoperative cardiac risk factors associated with in-hospital mortality in elderly patients without heart failure undergoing hip fracture surgery: a single-centre study.

机构信息

Health Sciences University, Sultan 2, Abdülhamid Han Training and Research Hospital, Department of Cardiology, Uskudar, Turkey

Health Sciences University, Sultan 2, Abdülhamid Han Training and Research Hospital, Department of Cardiology, Uskudar, Turkey.

出版信息

Postgrad Med J. 2021 Nov;97(1153):701-705. doi: 10.1136/postgradmedj-2020-138679. Epub 2020 Sep 10.

Abstract

INTRODUCTION

In the present study, our aim was to ascertain the preoperative cardiac risk factors related to the in-hospital mortality in the elderly patients (aged over 65 years) who required preoperative cardiology consultation for hip fracture surgery.

MATERIAL AND METHODS

The present study was a retrospective, single-centre study, which enrolled consecutive elderly patients without heart failure scheduled for hip fracture surgery in our institution. In all patients, an anesthesiologist performed a detailed preoperative evaluation and decided the need for the cardiac consultation. Patients underwent preoperative cardiac evaluation by a trained cardiologist using the algorithms proposed in the recent preoperative guidelines. The in-hospital mortality was the main outcome of the study.

RESULTS

In total, 277 elderly patients undergoing hip fracture surgery were enrolled in this analysis. The overall in-hospital mortality rate was 12.1% (n=30 cases). In a multivariate analysis, we found that insulin dependency, cancer, urea, presence of atrial fibrillation (AF) (OR: 3.906; 95% CI 1.470 to 10.381; p=0.006) and pulmonary artery systolic pressure (PASP) (OR: 1.057; 95% CI 1.016 to 1.100; p=0.006) were the predictors of in-hospital mortality. The receiver operating characteristic curve analysis revealed that the optimal value of PASP in predicting the in-hospital mortality was 35 mm Hg (area under the curve=0.71; 95% CI 0.60 to 0.81, p<0.001) with sensitivity of 87.7% and specificity of 59.5%.

CONCLUSION

The present research found that the preoperative cardiac risk factors, namely AF and PASP, might be associated with increased in-hospital mortality in elderly patients without heart failure undergoing hip fracture surgery.

摘要

简介

本研究旨在确定与因髋部骨折手术而接受术前心脏病学咨询的老年患者(年龄>65 岁)院内死亡率相关的术前心脏危险因素。

材料与方法

本研究为回顾性单中心研究,纳入了我院计划行髋部骨折手术且无心力衰竭的连续老年患者。所有患者均由麻醉师进行详细的术前评估,并决定是否需要心脏咨询。患者由经过培训的心脏病专家使用最近术前指南中提出的算法进行术前心脏评估。本研究的主要结局为院内死亡率。

结果

共纳入 277 例行髋部骨折手术的老年患者进行本分析。总的院内死亡率为 12.1%(n=30 例)。多变量分析发现,胰岛素依赖、癌症、尿素、心房颤动(AF)的存在(OR:3.906;95%CI 1.470 至 10.381;p=0.006)和肺动脉收缩压(PASP)(OR:3.906;95%CI 1.470 至 10.381;p=0.006)是院内死亡率的预测因素。受试者工作特征曲线分析显示,PASP 预测院内死亡率的最佳值为 35mmHg(曲线下面积=0.71;95%CI 0.60 至 0.81,p<0.001),敏感性为 87.7%,特异性为 59.5%。

结论

本研究发现,术前心脏危险因素,即 AF 和 PASP,可能与无心力衰竭行髋部骨折手术的老年患者院内死亡率增加相关。

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