减阻聚合物可改善 SCD 小鼠的肝血管阻塞。
Drag-reducing polymers improve hepatic vaso-occlusion in SCD mice.
机构信息
Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA.
McGowan Center for Regenerative Medicine, Pittsburgh, PA.
出版信息
Blood Adv. 2020 Sep 22;4(18):4333-4336. doi: 10.1182/bloodadvances.2020002779.
Abstract
Nanomolar concentrations of drag-reducing polymer (DRP) reduce vaso-occlusion in the liver of sickle cell disease (SCD) mice. The potential for DRP as a rheology-based treatment/therapy for SCD warrants further study.
摘要
纳米摩尔浓度的减阻聚合物 (DRP) 可减少镰状细胞病 (SCD) 小鼠肝脏中的血管阻塞。DRP 作为一种基于流变学的 SCD 治疗方法具有进一步研究的潜力。
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