中国成年人心电图异常的流行率及相关因素:一项横断面研究。

Prevalences and associated factors of electrocardiographic abnormalities in Chinese adults: a cross-sectional study.

机构信息

Department of Endocrinology, China-Japan Friendship Hospital, Beijing, China.

Department of Cardiology, China-Japan Friendship Hospital, Beijing, China.

出版信息

BMC Cardiovasc Disord. 2020 Sep 11;20(1):414. doi: 10.1186/s12872-020-01698-5.

Abstract

BACKGROUND

Electrocardiogram (ECG) is widely used to screen cardiac diseases. To date, no large population study has provided estimates of the prevalences of ECG findings in China. We aim to investigate the prevalences and associated factors of ECG abnormalities in a general population of Chinese adults.

METHODS

ECG data were obtained from 34,965 participants in the 2007-2008 China National Diabetes and Metabolic Disorders Study. ECG abnormalities were classified according to the Minnesota coding (MC) criteria. Prevalences of variant ECG abnormalities were calculated. The associations between ECG abnormalities and gender, age and other risk factors for cardiovascular diseases (CVD) were analyzed by multivariate logistic regression test.

RESULTS

The prevalences of major arrhythmias were 1.70, 2.37 and 1.04% in the whole population, men and women, respectively. Atrial fibrillation/flutter was found in 0.35% of men and 0.20% of women. ST depression and T abnormalities accounted for 10.96, 7.54 and 14.32% in the whole population, men and women, respectively. Independent of gender and other CVD risk factors, older age significantly increased the odds of having atrial fibrillation/flutter, complete left bundle branch block, complete right bundle branch block, sinus tachycardia, atrial/junctional/ventricular premature beats, ST depression and T abnormalities, tall R wave left, left/right atrial hypertrophy, left axis deviation and low voltage. Hypertension, overweight, obesity and hypercholesterolemia all independently increased the odds of having ST depression and T abnormalities. History of cardiovascular/cerebrovascular diseases was positively associated with major arrhythmias, ST depression and T abnormalities and tall R wave left.

CONCLUSIONS

This study provides estimates of the prevalences of ECG findings in a large population of Chinese adults. Gender, age, CVD risk factors and history of cardiovascular/cerebrovascular diseases were significantly associated with ECG abnormalities.

摘要

背景

心电图(ECG)广泛用于筛查心脏疾病。迄今为止,尚无大型人群研究提供中国人群心电图结果的患病率估计。本研究旨在调查中国成年人群中心电图异常的患病率及其相关因素。

方法

从 2007-2008 年中国糖尿病和代谢紊乱研究中的 34965 名参与者中获取心电图数据。根据明尼苏达编码(MC)标准对心电图异常进行分类。计算各种心电图异常的患病率。采用多变量 logistic 回归检验分析心电图异常与性别、年龄及心血管疾病(CVD)其他危险因素之间的关系。

结果

在整个人群、男性和女性中,主要心律失常的患病率分别为 1.70%、2.37%和 1.04%。男性中房颤/房扑的患病率为 0.35%,女性中为 0.20%。ST 段压低和 T 波异常在整个人群、男性和女性中的比例分别为 10.96%、7.54%和 14.32%。不论性别和其他 CVD 危险因素如何,年龄较大与房颤/房扑、完全左束支传导阻滞、完全右束支传导阻滞、窦性心动过速、房性/结性/室性期前收缩、ST 段压低和 T 波异常、左胸高 R 波、左/右心房肥厚、左轴偏和低电压的发生几率增加显著相关。高血压、超重、肥胖和高胆固醇血症均与 ST 段压低和 T 波异常的发生几率增加独立相关。心血管/脑血管疾病史与主要心律失常、ST 段压低和 T 波异常及左胸高 R 波显著相关。

结论

本研究提供了中国成年人大型人群中心电图结果的患病率估计。性别、年龄、CVD 危险因素和心血管/脑血管疾病史与心电图异常显著相关。

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