De Bacquer D, De Backer G, Kornitzer M
Department of Public Health, University of Ghent, De Pintelaan 185, B-9000 Gent, Belgium.
Heart. 2000 Dec;84(6):625-33. doi: 10.1136/heart.84.6.625.
To obtain accurate estimates of the prevalence of ECG abnormalities in the general population and to describe them in relation to age, sex, and some lifestyle related factors.
The results were obtained from the records of 47 358 men and women participating in four large Belgian epidemiological studies during the past 30 years. All tracings were read and coded by two trained cardiologists on the basis of Minnesota code criteria.
Prevalences of coronary heart disease and abnormal ECG findings rose exponentially with age in both sexes, with the exception of atrioventricular block and the Wolff-Parkinson-White (WPW) syndrome. Major ECG findings were observed in 6.0% of all men and 4.3% of women, resulting in a significant adjusted sex ratio of 1.66 (95% confidence interval 1.46 to 1.88). The prevalence of minor ECG changes was slightly higher among men (10.4% v 9.5% in women). The occurrence of ischaemia-like findings on the ECG was comparable between men and women (9.0% v 9.8%). Independent of age, smoking, obesity, diabetes, employment status, positive history of angina or infarction, and region, there were significantly higher prevalences of Q/QS patterns, left ventricular hypertrophy, left axis deviation, arrhythmias, and atrial fibrillation or flutter in men than in women. Right bundle branch block and WPW syndrome both occurred 3.5 times more often in men, while the prevalence of left bundle branch block was comparable between the sexes.
The large sample size allowed a precise description of the most important ECG abnormalities. These are not rare in the adult population and most are strongly age related. Sex differences occur with some, but not all, abnormalities. The less common ECG abnormalities were more often observed among men.
准确估计普通人群中心电图异常的患病率,并描述其与年龄、性别及一些生活方式相关因素的关系。
结果来自于过去30年参与四项大型比利时流行病学研究的47358名男性和女性的记录。所有心电图由两名经过培训的心脏病专家根据明尼苏达编码标准进行解读和编码。
冠心病和异常心电图表现的患病率在两性中均随年龄呈指数上升,但房室传导阻滞和预激综合征(WPW)除外。在所有男性中,6.0%观察到主要心电图表现,女性为4.3%,调整后的性别比为1.66(95%置信区间1.46至1.88),差异有统计学意义。男性中轻微心电图改变的患病率略高于女性(10.4%对9.5%)。心电图上缺血样表现的发生率在男性和女性中相当(9.0%对9.8%)。独立于年龄、吸烟、肥胖、糖尿病、就业状况、心绞痛或心肌梗死的阳性病史以及地区,男性中Q/QS波型、左心室肥厚、电轴左偏、心律失常以及心房颤动或扑动的患病率显著高于女性。右束支传导阻滞和WPW综合征在男性中的发生率均为女性的3.5倍,而左束支传导阻滞的患病率在两性中相当。
大样本量使得能够精确描述最重要的心电图异常情况。这些异常在成年人群中并不罕见,且大多数与年龄密切相关。部分而非所有异常存在性别差异。较不常见的心电图异常在男性中更常被观察到。