Hussein Albadr, Al Khalil Khaled, Bawazir Yasser M
Medicine/Rheumatology, King Fahad General Hospital, Madina, SAU.
Internal Medicine/Rheumatology, King Abdulaziz University, Jeddah, SAU.
Cureus. 2020 Aug 10;12(8):e9643. doi: 10.7759/cureus.9643.
Granulomatosis with polyangiitis is a small vessel vasculitis with a wide spectrum of presentation, ranging from limited disease to life-threatening situation such as alveolar hemorrhage. Immunosuppression is the corner stone of the treatment and if left untreated, the death toll increases dramatically. We presented a case of granulomatosis with polyangiitis, presented with alveolar hemorrhage associated with COVID-19 infection. The patient admitted to the intensive care unit, received pulse steroids, plasmapheresis and intravenous immunoglobulin. She was not given further immunosuppression because of the coexisting COVID-19. Up to our knowledge, this is the first reported case of alveolar hemorrhage secondary to granulomatosis with polyangiitis coexisting with COVID-19 infection.
肉芽肿性多血管炎是一种小血管血管炎，临床表现多样，从局限性疾病到危及生命的情况，如肺泡出血。免疫抑制是治疗的基石，如果不进行治疗，死亡率会急剧上升。我们报告了一例肉芽肿性多血管炎病例，该病例表现为与新型冠状病毒肺炎感染相关的肺泡出血。患者入住重症监护病房，接受了冲击剂量的类固醇、血浆置换和静脉注射免疫球蛋白治疗。由于同时感染新型冠状病毒肺炎，未给予进一步的免疫抑制治疗。据我们所知，这是首例报告的肉芽肿性多血管炎继发肺泡出血合并新型冠状病毒肺炎感染的病例。
