Federal Institute of Sertão Pernambuco - Campus Floresta-PE, Brazil.
Center for Drug, Food and Drug Analysis, Federal University of the São Francisco Valley, Petrolina, Brazil.
Nat Prod Res. 2022 Apr;36(7):1893-1897. doi: 10.1080/14786419.2020.1813135. Epub 2020 Sep 14.
(Willd.) Poir., popularly known as "black jurema", is a plant that is predominant in the Caatinga Biome. Drinks used in indigenous rituals use the barks of this plant that are rich in -dimethyltryptamine (DMT), an indolic alkaloid responsible for hallucinogenic activity. The objective of this study was to evaluate the chemical and pharmacognostic characteristics of the bark using nuclear magnetic resonance(NMR) analytical techniques and gas chromatography coupled to mass spectrometry(GC-MS) to identify and quantify the DMT present in the extract of . The results showed that the plant material is within the recommended standards. Both NMR and GC-MS techniques were able to identify and quantify the DMT with NMR being the best option. In conclusion this study contributes significantly to the standardization of the studied plant material and assists in the use of these data for future development of products from on this forestry species.
(Willd.) Poir.,俗称“黑朱玛”,是一种在卡廷加生物群系中占优势的植物。用于土著仪式的饮料使用这种植物的树皮,其富含 -二甲基色胺(DMT),这是一种吲哚生物碱,负责致幻活性。本研究的目的是使用核磁共振(NMR)分析技术和气相色谱-质谱联用(GC-MS)评估树皮的化学和生药学特性,以鉴定和定量存在于 提取物中的 DMT。结果表明,植物材料符合建议标准。NMR 和 GC-MS 技术都能够识别和定量 DMT,其中 NMR 是最佳选择。总之,这项研究对所研究的植物材料的标准化有重要贡献,并有助于为未来从这种林业物种开发产品提供这些数据。