一名患有2019冠状病毒病（COVID-19）心肌炎患者的心源性栓塞性中风：病例报告
Cardioembolic Stroke in a Patient with Coronavirus Disease of 2019 (COVID-19) Myocarditis: A Case Report.
作者信息
Ford James S, Holmes James F, Jones Russell F
机构信息
UC Davis Health, Department of Emergency Medicine, Sacramento, California.
出版信息
Clin Pract Cases Emerg Med. 2020 Aug;4(3):332-335. doi: 10.5811/cpcem.2020.6.47856.
Abstract
INTRODUCTION
There is a growing body of literature detailing coronavirus 2019 (COVID-19) cardiovascular complications and hypercoagulability, although little has been published on venous or arterial thrombosis risk.
CASE REPORT
In this report, we present a single case of cardioembolic stroke in the setting of COVID-19 related myocarditis, diagnosed via cardiac magnetic resonance imaging and echocardiography. COVID-19 infection was confirmed via a ribonucleic acid polymerase chain reaction assay.
CONCLUSION
Further research is needed to evaluate the hypercoagulable state of patients with COVID-19 to determine whether prophylactic anticoagulation may be warranted to prevent intracardiac thrombi and cardioembolic disease in patients with COVID-19 related myocarditis.
摘要
引言
尽管关于静脉或动脉血栓形成风险的报道较少，但越来越多的文献详细阐述了2019冠状病毒病（COVID-19）的心血管并发症和高凝状态。
病例报告
在本报告中，我们介绍了1例在COVID-19相关心肌炎背景下发生的心源性栓塞性中风病例，通过心脏磁共振成像和超声心动图确诊。通过核糖核酸聚合酶链反应检测确诊为COVID-19感染。
结论
需要进一步研究以评估COVID-19患者的高凝状态，以确定对于COVID-19相关心肌炎患者，预防性抗凝是否有助于预防心内血栓和心源性栓塞性疾病。
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本文引用的文献
1
[Clinical and coagulation characteristics of 7 patients with critical COVID-2019 pneumonia and acro-ischemia].7例危重型新型冠状病毒肺炎合并肢端缺血患者的临床及凝血特征
Zhonghua Xue Ye Xue Za Zhi. 2020 Mar 28;41(0):E006. doi: 10.3760/cma.j.issn.0253-2727.2020.0006.
2
Potential Effects of Coronaviruses on the Cardiovascular System: A Review.冠状病毒对心血管系统的潜在影响：综述。
JAMA Cardiol. 2020 Jul 1;5(7):831-840. doi: 10.1001/jamacardio.2020.1286.
3
Cardiovascular Considerations for Patients, Health Care Workers, and Health Systems During the COVID-19 Pandemic.心血管考虑因素在 COVID-19 大流行期间的患者、医护人员和卫生系统。
J Am Coll Cardiol. 2020 May 12;75(18):2352-2371. doi: 10.1016/j.jacc.2020.03.031. Epub 2020 Mar 19.
4
Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study.中国武汉成人 COVID-19 住院患者的临床病程和死亡危险因素：一项回顾性队列研究。
Lancet. 2020 Mar 28;395(10229):1054-1062. doi: 10.1016/S0140-6736(20)30566-3. Epub 2020 Mar 11.
5
Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China.基于对来自中国武汉的150名患者数据的分析得出的COVID-19相关死亡的临床预测因素。
Intensive Care Med. 2020 May;46(5):846-848. doi: 10.1007/s00134-020-05991-x. Epub 2020 Mar 3.
6
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J Thromb Haemost. 2020 Apr;18(4):844-847. doi: 10.1111/jth.14768. Epub 2020 Mar 13.
7
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8
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Lancet. 2020 Feb 15;395(10223):497-506. doi: 10.1016/S0140-6736(20)30183-5. Epub 2020 Jan 24.
9
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Ann Emerg Med. 2012 Dec;60(6):766-76. doi: 10.1016/j.annemergmed.2012.07.119. Epub 2012 Aug 31.
10
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