合成具有药理相关性的 1,2,3-三唑及其类似物的综述。
Synthesis of Pharmacological Relevant 1,2,3-Triazole and Its Analogues-A Review.
机构信息
Scrips Pharma, Mallapur, Hyderabad, Telangana-500 076, India.
Department of Chemistry, Acharya Nagarjuna University, Guntur-522510, AP, India.
出版信息
Curr Org Synth. 2021;18(2):101-124. doi: 10.2174/1570179417666200914142229.
Abstract
In this review, authors focus mostly on the various synthetic strategies developed so far for 1,2,3- triazole scaffold and its derivatives via different approaches such as metal-free, metal assisted or bimetallic. A brief overview of applications of the very important 1,2,3-triazole scaffold along with pharmacological activity is also discussed. Synthetic strategies are updated until June 2020.
摘要
在这篇综述中，作者主要关注迄今为止通过不同方法（如无金属、金属辅助或双金属）开发的 1,2,3-三唑支架及其衍生物的各种合成策略。还简要讨论了非常重要的 1,2,3-三唑支架的应用及其药理学活性。合成策略更新至 2020 年 6 月。
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