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季节性冠状病毒的保护免疫作用是短暂的。

Seasonal coronavirus protective immunity is short-lasting.

机构信息

Laboratory of Experimental Virology, Department of Medical Microbiology and Infection Prevention, Amsterdam Infection & Immunity Institute, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.

INGENASA, Inmunología y Genética Aplicada S. A., Madrid, Spain.

出版信息

Nat Med. 2020 Nov;26(11):1691-1693. doi: 10.1038/s41591-020-1083-1. Epub 2020 Sep 14.

Abstract

A key unsolved question in the current coronavirus disease 2019 (COVID-19) pandemic is the duration of acquired immunity. Insights from infections with the four seasonal human coronaviruses might reveal common characteristics applicable to all human coronaviruses. We monitored healthy individuals for more than 35 years and determined that reinfection with the same seasonal coronavirus occurred frequently at 12 months after infection.

摘要

当前 2019 年冠状病毒病(COVID-19)大流行中一个未解决的关键问题是获得性免疫的持续时间。从感染四种季节性人类冠状病毒中获得的见解可能揭示适用于所有人类冠状病毒的共同特征。我们对健康个体进行了超过 35 年的监测,并确定在感染后 12 个月经常发生同种季节性冠状病毒的再感染。

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