Quinti I, Papetti C, D'Offizi G, Cavagni G, Panchor M L, Lunardi C, Paganelli R
Department of Allergy and Clinical Immunology, University La Sapienza, Rome, Italy.
Allerg Immunol (Paris). 1988 Feb;20(2):41, 43-4.
Involvement of sub-classes of IgG that are specific for food allergens in anaphylactoid reactions and some manifestations of atopy no longer needs to be shown. Accordingly, sub-classes of IgG specific for ovalbumin (OVA) and beta-lactoglobulin (BLG) were compared in healthy subjects and those who presented with an intolerance or food allergy to OVA and BLG to decide whether a restrictive diet was necessary. The four sub-classes of IgG1, IgG2, IgG3 and IgG4 were isolated in all the groups. IgG4 was highest in the allergic subjects and the IgG sub-class values were modified by the diet differently in each group. Unfortunately, the small number of subjects does not allow the formation of a definite conclusion to this study.
