Institute of Veterinary Medicine, Xinjiang Academy of Animal Sciences, Urumqi, China.
School of Public Health, Sun Yat-sen University, Guangzhou, China.
Vector Borne Zoonotic Dis. 2020 Dec;20(12):882-887. doi: 10.1089/vbz.2020.2630. Epub 2020 Sep 16.
Wild ruminants are at risk for zoonotic pathogen infection as a result of interactions with domestic animals and humans. One way to assess the level of a wild ruminant disease in a population is to determine the seroprevalence of the pathogen of interest. The objective of this study was to determine the seroprevalence of five zoonotic pathogens in wild ruminants in Xinjiang, Northwest China. In 2009 and 2011-2015, 258 wild ruminant sera samples were collected from various species. Samples were obtained from 30 Siberian ibexes, 94 goitered gazelles, 6 Tibetan antelopes, 32 argali sheep, 16 roe deer, 20 blue sheep, 56 red deer, and 4 wild yaks, in 10 regions of Xinjiang. Samples were tested using antibodies against ., , , , and West Nile virus. Seropositivity was detected for all five pathogens, with detection rates of ., , , and West Nile virus of 2.3% (95% confidence interval [CI], 0.5-4.2%), 6.2% (95% CI, 3.3-9.1%), 7.8% (95% CI, 4.5-11.0%), 2.3% (95% CI, 0.5-4.2%), and 0.8% (95% CI, 0-1.8%), respectively. The level of pathogens differed for different species and different regions. The results indicate that seropositivity to zoonotic pathogens is common among wild ruminants in Xinjiang, Northwest China, with and detected at the highest levels. This study provides a baseline for future assessment of spillover events.
野生动物由于与家畜和人类的相互作用而面临人畜共患病原体感染的风险。评估人群中野生动物疾病水平的一种方法是确定感兴趣的病原体的血清流行率。本研究的目的是确定中国西北新疆地区野生反刍动物五种人畜共患病原体的血清流行率。2009 年和 2011-2015 年，从各种物种中采集了 258 份野生反刍动物血清样本。从新疆 10 个地区的 30 只西伯利亚野山羊、94 只野牦牛、6 只藏羚羊、32 只盘羊、16 只獐鹿、20 只青羊、56 只马鹿和 4 头野牦牛中采集了样本。使用针对 、 、 、 和西尼罗河病毒的抗体对样本进行了检测。所有五种病原体均检测到了血清阳性，检出率分别为 、 、 、 和西尼罗河病毒为 2.3%（95%置信区间[CI]，0.5-4.2%）、6.2%（95% CI，3.3-9.1%）、7.8%（95% CI，4.5-11.0%）、2.3%（95% CI，0.5-4.2%）和 0.8%（95% CI，0-1.8%）。不同物种和不同地区的病原体水平存在差异。结果表明，新疆野生反刍动物对人畜共患病原体的血清阳性率较高，其中 和 检测率最高。本研究为未来溢出事件的评估提供了基线。
