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脑脊液确诊的新型冠状病毒肺炎相关脑炎治疗成功。

Cerebrospinal fluid confirmed COVID-19-associated encephalitis treated successfully.

作者信息

Kamal Yasmine Mohamed, Abdelmajid Yasmin, Al Madani Abubaker Abdul Rahman

机构信息

Neurology, Dubai Health Authority, Dubai, United Arab Emirates.

Neurology, Dubai Health Authority, Dubai, United Arab Emirates

出版信息

BMJ Case Rep. 2020 Sep 16;13(9):e237378. doi: 10.1136/bcr-2020-237378.

Abstract

The COVID-19 pandemic that attracted global attention in December 2019 is well known for its clinical picture that is consistent with respiratory symptoms. Currently, the available medical literature describing the neurological complications of COVID-19 is gradually emerging. We hereby describe a case of a 31-year-old COVID-19-positive patient who was admitted on emergency basis. His clinical presentation was primarily neurological, rather than the COVID-19's classical respiratory manifestations. He presented with acute behavioural changes, severe confusion and drowsiness. The cerebrospinal fluid analysis was consistent with COVID-19 encephalitis, as well as the brain imaging. This experience confirms that neurological manifestations might be expected in COVID-19 infections, despite the absence of significant respiratory symptoms. Whenever certain red flags are raised, physicians who are involved in the management of COVID-19 should promptly consider the possibility of encephalitis. Early recognition of COVID-19 encephalitis and timely management may lead to a better outcome.

摘要

2019年12月引起全球关注的新冠疫情,以其与呼吸道症状相符的临床表现而闻名。目前,描述新冠病毒神经并发症的现有医学文献正逐渐出现。我们在此描述一例31岁的新冠病毒检测呈阳性的患者,该患者因急诊入院。他的临床表现主要是神经方面的,而非新冠的典型呼吸道表现。他表现出急性行为改变、严重意识模糊和嗜睡。脑脊液分析以及脑部影像学检查结果均与新冠脑炎相符。这一病例证实,尽管没有明显的呼吸道症状,但新冠病毒感染仍可能出现神经方面的表现。一旦出现某些警示信号,参与新冠治疗的医生应及时考虑脑炎的可能性。早期识别新冠脑炎并及时治疗可能会带来更好的结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b33/7497137/05f72eb28683/bcr-2020-237378f01.jpg

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