Argoudelis A D, Baczynskyj L, Mizsak S A, Shilliday F B, Spinelli P A, DeZwaan J
J Antibiot (Tokyo). 1987 Apr;40(4):419-36. doi: 10.7164/antibiotics.40.419.
Paldimycin (antibiotic 273a1) and antibiotic 273a2 as well as their individual components, paldimycins A (273a1 alpha) and B (273a1 beta) and antibiotics 273a2 alpha and 273a2 beta were synthesized from paulomycin, paulomycin A and paulomycin B, respectively, by reacting with N-acetyl-L-cysteine. The semisynthetic antibiotics had chromatographic behavior (TLC, HPLC) and physical and chemical properties identical to the properties of the corresponding antibiotics produced by Streptomyces paulus.
帕地霉素（抗生素273a1）和抗生素273a2及其各自的组分，帕地霉素A（273a1α）和B（273a1β）以及抗生素273a2α和273a2β分别由保洛霉素、保洛霉素A和保洛霉素B与N - 乙酰 - L - 半胱氨酸反应合成。这些半合成抗生素具有与保罗链霉菌产生的相应抗生素相同的色谱行为（薄层色谱法、高效液相色谱法）以及物理和化学性质。
