In vitro evaluation of the new paulomycin antibiotic paldimycin.

The comparative in vitro activity of paldimycin, a new antibiotic, was evaluated against 215 gram-positive bacteria. Activity of the compound was greater in nutrient agar of pH 6.8 than in Mueller-Hinton agar. All strains of staphylococci, streptococci, enterococci and Listeria monocytogenes were inhibited at concentrations less than or equal to 2 micrograms/ml. Activity of the new drug was generally comparable to that of vancomycin.