Dougas Georgios, Mavrouli Maria, Tsakris Athanassios, Billinis Charalambos, Papaparaskevas Joseph
Department of Microbiology, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Department of Microbiology and Parasitology, Faculty of Veterinary Science, University of Thessaly, 43100 Karditsa, Greece.
Trop Med Infect Dis. 2020 Sep 16;5(3):145. doi: 10.3390/tropicalmed5030145.
are the causative agents of murine typhus and cat-scratch disease, respectively. A small-scale survey (N = 202) was conducted in the Attica region, Greece, for determining the prevalence rates of IgG antibodies against and by indirect fluorescence antibody test. IgG against and were present in 17.8% (36/202) and 4.5% (9/202) of the participants, respectively; co-occurring IgG against both and were detected in 3.5% (7/202), whereas only anti- IgG in 14.3% (29/202), and only anti- IgG in 1.0% (2/202). Titres 1/64, 1/128, 1/256, and 1/512, of anti- IgG were identified in 6.4%, 4.5%, 4.5%, and 2.4%, whereas titres 1/40 and 1/80 of anti- IgG were detected in 4.0%, and 0.5%, respectively. A positive association of anti- IgG prevalence with a coastal area featuring a major seaport ( = 0.009) and with younger age ( = 0.046) was identified. The findings of this survey raise concern for exposure of the population of Attica to and , which should be considered in the differential diagnosis when compatible symptoms are present. Our results also suggest that seaports may represent high-risk areas for exposure to spp.
分别是鼠型斑疹伤寒和猫抓病的病原体。在希腊阿提卡地区进行了一项小规模调查（N = 202），通过间接荧光抗体试验确定针对[具体病原体1]和[具体病原体2]的IgG抗体患病率。针对[具体病原体1]和[具体病原体2]的IgG分别存在于17.8%（36/202）和4.5%（9/202）的参与者中；同时检测到针对[具体病原体1]和[具体病原体2]的IgG共存在3.5%（7/202）中，而仅抗[具体病原体1] IgG存在于14.3%（29/202）中，仅抗[具体病原体2] IgG存在于1.0%（2/202）中。抗[具体病原体1] IgG滴度为1/64、1/128、1/256和1/512的分别占6.4%、4.5%、4.5%和2.4%，而抗[具体病原体2] IgG滴度为1/40和1/80的分别占4.0%和0.5%。确定抗[具体病原体1] IgG患病率与有主要海港的沿海地区（P = 0.009）和较年轻年龄（P = 0.046）呈正相关。这项调查结果引发了对阿提卡地区人群接触[具体病原体1]和[具体病原体2]的担忧，当出现相容症状时，在鉴别诊断中应予以考虑。我们的结果还表明海港可能是接触[具体病原体属]的高风险区域。
