Nimni-Cordoba Tissue Engineering and Drug Discovery Laboratory, Department of Surgery, University of Southern California, Los Angeles, CA 90033, United States.
Nimni-Cordoba Tissue Engineering and Drug Discovery Laboratory, Department of Surgery, University of Southern California, Los Angeles, CA 90033, United States.
J Infect Public Health. 2020 Dec;13(12):1811-1817. doi: 10.1016/j.jiph.2020.08.014. Epub 2020 Sep 10.
The pandemic of novel coronavirus caused COVID-19 had resulted in a high number of hospitalizations and deaths and caused a devastating toll on human and society health. The symptoms of the infected patients vary significantly, from life-threatening to mild or even asymptomatic. This clinical observation led to hypothesize on the critical role of host innate immunity in the disease development and progression. As the first defense barrier against microorganisms, the innate immune reaction determines not only the viral infection rate but also immune-mediated response. Therefore, promote healthy behaviors to enhance innate immunity with functional food and nutritional agents may be a rational strategy for minimizing damages caused by viruses to global health.
新型冠状病毒引发的大流行导致 COVID-19 导致大量住院和死亡，对人类和社会健康造成了毁灭性的影响。感染患者的症状差异很大，从危及生命到轻微甚至无症状。这种临床观察导致人们假设宿主固有免疫在疾病发展和进展中起关键作用。作为抵御微生物的第一道防线，固有免疫反应不仅决定了病毒感染率，还决定了免疫介导的反应。因此，促进健康行为，利用功能性食品和营养剂增强固有免疫可能是减轻病毒对全球健康造成损害的合理策略。
