Marchi Giacomo, Vianello Alice, Crisafulli Ernesto, Maroccia Alessio, Crinò Stefano Francesco, Pecori Sara, Zamboni Giulia A, Mazzaferri Fulvia, Tacconelli Evelina, Girelli Domenico
Department of Medicine, Internal Medicine Unit, University Hospital of Verona, Verona, Italy.
Department of Medicine, Gastroenterology and Digestive Endoscopy Unit, University Hospital of Verona, Verona, Italy.
Mediterr J Hematol Infect Dis. 2020 Sep 1;12(1):e2020060. doi: 10.4084/MJHID.2020.060. eCollection 2020.
COVID-19 is a new pandemic disease whose pathophysiology and clinical description are still not completely defined. Besides respiratory symptoms and fever, gastrointestinal (GI) symptoms (including especially anorexia, diarrhea, and abdominal pain) represent the most frequent clinical manifestations. Emerging data point out that severe SARS-CoV-2 infection causes an immune dysregulation, which in turn may favor other infections. Here we describe a patient with severe COVID-19 pneumonia who developed in the resolving phase abdominal pain associated with cytomegalovirus (CMV)-induced duodenitis with bleeding and pancreatitis. A high level of suspicion toward multiple infections, including CMV, should be maintained in COVID-19 patients with heterogeneous clinical manifestations.
新型冠状病毒肺炎（COVID-19）是一种新出现的大流行性疾病，其病理生理学和临床描述仍未完全明确。除呼吸道症状和发热外，胃肠道（GI）症状（尤其是厌食、腹泻和腹痛）是最常见的临床表现。新出现的数据指出，严重的严重急性呼吸综合征冠状病毒2（SARS-CoV-2）感染会导致免疫失调，进而可能引发其他感染。在此，我们描述了一名患有严重COVID-19肺炎的患者，该患者在病情缓解期出现腹痛，伴有巨细胞病毒（CMV）诱导的十二指肠炎症伴出血和胰腺炎。对于临床表现各异的COVID-19患者，应高度怀疑包括CMV在内的多种感染。
