经颅直流电刺激（tDCS）与语言/认知干预对痴呆患者命名能力的联合影响：一项系统评价与Meta分析
Combined Effects of tDCS and Language/Cognitive Intervention on the Naming of Dementia Patients: A Systematic Review and Meta-Analysis.
作者信息
Byeon Haewon
机构信息
Department of Speech Language Pathology, College of Health Science, Honam University, Gwangju, Republic of Korea.
出版信息
Iran J Public Health. 2020 May;49(5):822-829.
BACKGROUND
The evidence of transcranial direct current stimulation (tDCS) treatment effects on dementia is still insufficient. This study aimed to prove the scientific basis of tDCS by conducting a meta-analysis of previous studies that examined the effects of tDCS on the naming of patients with dementia.
METHODS
The literature search was conducted for publications published from Jan 2000 to Jun 2019 using four academic databases (PubMed, Web of Science, MEDLINE, and Cochrane Library). This study found 129 publications by searching academic databases according to the PRISMA protocol. Among them, irrelevant studies were excluded, and finally, 4 studies were meta-analyzed.
RESULTS
The score of the quality assessment on five studies ranged from 21 to 26 points, rated good or better. Meta-analysis results, tDCS had no significant effect on the improvement of naming ability of dementia. On the other hand, the effect size of the tDCS intervention + language/cognitive training was significant 'large effect (SMD=0.72, 95% CI: 0.05, 1.39)'.
CONCLUSION
This combination of tDCS and language/cognitive training significantly improved the naming ability of dementia patients.
背景
经颅直流电刺激（tDCS）治疗痴呆症效果的证据仍不充分。本研究旨在通过对先前研究进行荟萃分析，以检验tDCS对痴呆症患者命名能力的影响，从而证明tDCS的科学依据。
方法
使用四个学术数据库（PubMed、科学网、医学在线数据库和考克兰图书馆）检索2000年1月至2019年6月发表的文献。本研究根据PRISMA协议在学术数据库中检索到129篇出版物。其中，排除无关研究，最终对4项研究进行荟萃分析。
结果
五项研究的质量评估得分在21至26分之间，评定为良好或更好。荟萃分析结果显示，tDCS对改善痴呆症患者的命名能力无显著影响。另一方面，tDCS干预+语言/认知训练的效应量显著为“大效应（标准化均数差=0.72，95%置信区间：0.05，1.39）”。
结论
tDCS与语言/认知训练相结合可显著提高痴呆症患者的命名能力。
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