微生物简介：种复合体。
Microbe Profile: species complex.
机构信息
Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Republic of Korea.
Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710, USA.
出版信息
Microbiology (Reading). 2020 Sep;166(9):797-799. doi: 10.1099/mic.0.000973.
is a lethal fungus disguised in a polysaccharide coat. It can remain dormant in the host for decades prior to reactivation, causing systemic cryptococcosis in humans and other mammals. deploys a multitude of traits to adapt to and survive within the host, including immunosuppression, an ability to replicate intra- and extra-cellularly in phagocytes, changes in morphology and ploidy, a predilection to infect the CNS, and the capacity to utilize neurotransmitters and unique carbon sources available in the brain. These pathogenic strategies displayed by this fungus might have evolved through its interactions with microbial predators in the environment.
荚膜组织胞浆菌是一种致命的真菌，伪装在多糖荚膜中。它可以在宿主体内潜伏数十年，然后重新激活，导致人类和其他哺乳动物发生系统性隐球菌病。荚膜组织胞浆菌通过多种特性来适应和在宿主中生存，包括免疫抑制、在吞噬细胞内外复制的能力、形态和倍性的改变、偏爱感染中枢神经系统，以及利用神经递质和大脑中独特的碳源的能力。这种真菌表现出的这些致病策略可能是通过它与环境中的微生物捕食者的相互作用而进化而来的。
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