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Low-grade inflammation is negatively associated with physical Health-Related Quality of Life in healthy individuals: Results from The Danish Blood Donor Study (DBDS).低水平炎症与健康个体的身体健康相关生活质量呈负相关：来自丹麦献血者研究（DBDS）的结果。
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Dietary inflammatory index and its relationship with high-sensitivity C-reactive protein in Korean: data from the health examinee cohort.韩国人群的饮食炎症指数及其与高敏C反应蛋白的关系：来自健康体检队列的数据。
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Association between dietary inflammatory index and inflammatory markers in the HELENA study.赫勒纳研究中饮食炎症指数与炎症标志物之间的关联。
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饮食炎症指数与膝关节骨关节炎患者的疼痛强度及生活质量的某些组成部分相关。

Dietary inflammatory index is associated with pain intensity and some components of quality of life in patients with knee osteoarthritis.

作者信息

Toopchizadeh Vahideh, Dolatkhah Neda, Aghamohammadi Dawood, Rasouli Mahrokh, Hashemian Maryam

机构信息

Physical Medicine and Rehabilitation Research Center, Aging Research Institute, Tabriz University of Medical Science, Azadi Ave., Tabriz, Iran.

Palliative Care Medicine Department, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.

出版信息

BMC Res Notes. 2020 Sep 21;13(1):448. doi: 10.1186/s13104-020-05277-x.

DOI:10.1186/s13104-020-05277-x
PMID:32958008
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7507718/
Abstract

OBJECTIVES

We aim to measure dietary inflammatory index (DII) and its association with functional status, pain intensity and quality of life (QOL) in patients with knee osteoarthritis (KOA). Dietary information from 220 qualified patients with KOA was collected by a 168-item food frequency questionnaire. The functional status, pain intensity and QOL were evaluated by Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) questionnaire, Visual Analogue Scale (VAS) and SF36 questionnaire respectively.

RESULTS

Linear regression analysis showed that the DII was significantly associated with VAS (p = 0.040; β = 0.151), and physical function (p = 0.039; β = - 0.184), emotional wellbeing (p = 0.048; β = - 0.158) and pain (p = 0.020; β = 0.161) scales and physical health (p = 0.047; β = 0.110) subscale of QOL after adjusting for age, sex, body mass index, and physical activity. There was no significant differences concerning WOMAC across the DII tertiles with and without adjustment to probable confounders (P = 0.091 and 0.181, respectively). After adjustment, a significantly increased severe pain odds was observed in the highest tertile of DII score in comparison with the lowest tertile (OR tertile  = 1.55, 95% CI 1.04-2.31; P = 0.04).

摘要

目的

我们旨在测量饮食炎症指数（DII）及其与膝关节骨关节炎（KOA）患者功能状态、疼痛强度和生活质量（QOL）之间的关联。通过一份包含168个条目的食物频率问卷收集了220名符合条件的KOA患者的饮食信息。功能状态、疼痛强度和生活质量分别通过西安大略和麦克马斯特大学骨关节炎指数（WOMAC）问卷、视觉模拟量表（VAS）和SF36问卷进行评估。

结果

线性回归分析显示，在调整年龄、性别、体重指数和身体活动后，DII与VAS（p = 0.040；β = 0.151）、身体功能（p = 0.039；β = -0.184）、情绪健康（p = 0.048；β = -0.158）、疼痛（p = 0.020；β = 0.161）量表以及生活质量的身体健康子量表（p = 0.047；β = 0.110）显著相关。在调整或未调整可能的混杂因素的情况下，DII三分位数组之间的WOMAC无显著差异（分别为P = 0.091和0.181）。调整后，与最低三分位数相比，DII得分最高三分位数组中观察到严重疼痛的几率显著增加（三分位数比值比 = 1.55，95%可信区间1.04 - 2.31；P = 0.04）。