Qudus B Aroyehun Abdul, Abdul Razak Shariza, Palaniveloo Kishneth, Nagappan Thilahgavani, Suraiza Nabila Rahmah Nur, Wee Jin Gan, Chellappan Dinesh Kumar, Chellian Jestin, Kunnath Anil Philip
Nutrition and Dietetics Program, School of Health Sciences, Health Campus, Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia.
Institute of Ocean and Earth Sciences, Institute for Advanced Studies Building, University of Malaya, Wilayah Persekutuan, Kuala Lumpur 50603, Malaysia.
Foods. 2020 Sep 18;9(9):1313. doi: 10.3390/foods9091313.
(Forsskal) J. Agardh is a green seaweed used as food and folk medicine since ancient times in the Indo-Pacific region, particularly in southeast Asia. In this study, the proximate nutrient composition, phytochemical, anti-oxidant and anti-diabetic properties of sea grape collected from culture fishponds in Johor, Malaysia were analysed. The contents (dry weight basis) of carbohydrate, crude protein, crude lipids, ash and caloric value obtained were 33.42 ± 1.34%, 20.27 ± 0.14%, 4.20 ± 0.32%, 28.25 ± 0.27% and 2544.67 ± 7.04 cal g, respectively. The amino acid score (AAs) and biological protein value (213.43 mg g) indicated that presented a better protein quality. The most abundant fatty acids were C16:0 (palmitic acid: 63.27%), followed by C18:1 (oleic acid: 5.80%), and C18:2 ῳ6 (linoleic acid: 5.33%). The analysis of the ash content indicated that essential minerals and trace elements, such as Ca, Fe, and Mn, were present in the seaweed. The total phenolic content (TPC) and total flavonoid content (TFC) observed in the ethyl acetate extract were 17.88 ± 0.78 mg GAE g and 59.43 ± 2.45 mg QE g, respectively. The ethyl acetate extract of demonstrated notable anti-diabetic activity in diabetic induced rats. The low (100 mg kg) and high (200 mg kg) doses of cultivated extract exhibited a significant decrease ( < 0.05) in blood glucose levels while preventing weight loss, reducing plasma AST, ALT levels as a sign of hepatoprotective effect and recording albumin levels similar to positive control in diabetic induced rats. The results support the usefulness of cultivated as a potential functional food.
（福斯卡尔）琼枝藻是一种绿色海藻，自古以来在印度 - 太平洋地区，特别是东南亚地区被用作食物和民间药物。在本研究中，对从马来西亚柔佛州养殖鱼塘采集的海葡萄的近似营养成分、植物化学成分、抗氧化和抗糖尿病特性进行了分析。所获得的碳水化合物、粗蛋白、粗脂肪、灰分和热值的含量（以干重计）分别为33.42±1.34%、20.27±0.14%、4.20±0.32%、28.25±0.27%和2544.67±7.04卡路里/克。氨基酸评分（AAs）和生物蛋白值（213.43毫克/克）表明其蛋白质质量较好。最丰富的脂肪酸是C16:0（棕榈酸：63.27%），其次是C18:1（油酸：5.80%）和C18:2ω6（亚油酸：5.33%）。灰分含量分析表明，该海藻中存在钙、铁和锰等必需矿物质和微量元素。在乙酸乙酯提取物中观察到的总酚含量（TPC）和总黄酮含量（TFC）分别为17.88±0.78毫克没食子酸当量/克和59.43±2.45毫克芦丁当量/克。海葡萄的乙酸乙酯提取物在糖尿病诱导大鼠中表现出显著的抗糖尿病活性。低剂量（100毫克/千克）和高剂量（200毫克/千克）的养殖海葡萄提取物在糖尿病诱导大鼠中使血糖水平显著降低（P<0.05），同时防止体重减轻，降低血浆AST、ALT水平作为肝脏保护作用的标志，并记录与阳性对照相似的白蛋白水平。结果支持养殖海葡萄作为潜在功能性食品的实用性。
