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应用 CT 和 MRI 联合临床资料分析胆囊残余结石形成的相关因素。

Factors related to residual gallbladder calculi formation using computed tomography and magnetic resonance imaging combined with clinical data.

机构信息

Department of Radiology, Shandong Provincial Third Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.

Department of Hepatobiliary Surgery, Shandong Provincial Third Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.

出版信息

J Int Med Res. 2020 Sep;48(9):300060520958968. doi: 10.1177/0300060520958968.

Abstract

OBJECTIVE

We aimed to investigate risk factors related to remnant gallbladder (RGB) stones.

METHODS

This retrospective study included 73 patients with RGB, in groups with and without RGB calculi. Univariate analyses were used to identify nine variables associated with RGB calculi: sex, age, body mass index (BMI), time to detection, surgical method, length of RGB, angle of RGB and common hepatic duct (CHD), choledocholithiasis, and remnant cholecystitis. Multivariate logistic regression was performed to assess independent predictors of RGB stones. A receiver operating characteristic (ROC) curve was used to estimate model accuracy and determine cut-off values of independent predictors.

RESULTS

We enrolled 73 patients, 33 with and 40 without RGB stones. Univariate analyses showed that age, BMI, time to detection, length of RGB, angle of RGB and CHD were predictors for RGB calculi. Multivariate analyses indicated that time to detection, length of RGB, and angle of RGB and CHD were independent predictors for RGB calculi. The area under the ROC curve of the model was 0.940. Cut-off values of the three indicators were 1.5 years, 2.25 cm, and 22.5°, respectively.

CONCLUSION

Time to detection, length of RGB, and angle of RGB and CHD were independent predictors of RGB calculi.

摘要

目的

本研究旨在探讨与残余胆囊(RGB)结石相关的危险因素。

方法

本回顾性研究纳入了 73 例 RGB 患者,分为有 RGB 结石组和无 RGB 结石组。采用单因素分析确定与 RGB 结石相关的 9 个变量:性别、年龄、体重指数(BMI)、发现时间、手术方法、RGB 长度、RGB 与肝总管(CHD)的夹角、胆总管结石和残余胆囊炎。采用多因素逻辑回归分析评估 RGB 结石的独立预测因子。采用受试者工作特征(ROC)曲线评估模型准确性,并确定独立预测因子的截断值。

结果

本研究共纳入 73 例患者,其中 33 例有 RGB 结石,40 例无 RGB 结石。单因素分析显示,年龄、BMI、发现时间、RGB 长度、RGB 与 CHD 的夹角是 RGB 结石的预测因子。多因素分析表明,发现时间、RGB 长度和 RGB 与 CHD 的夹角是 RGB 结石的独立预测因子。该模型的 ROC 曲线下面积为 0.940。三个指标的截断值分别为 1.5 年、2.25cm 和 22.5°。

结论

发现时间、RGB 长度和 RGB 与 CHD 的夹角是 RGB 结石的独立预测因子。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c30c/7517991/583f068c6057/10.1177_0300060520958968-fig1.jpg

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