Chiba Akiko, Hatate Kaoru, Onomi Rurika, Kawashima Chiho, Hanada Masaaki, Moriyama Tomoe, Goto Akira, Yamagishi Norio
United Graduate School of Veterinary Sciences, Gifu University, Gifu 501-1193, Japan.
Veterinary Medical Center, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8550, Japan.
J Vet Med Sci. 2020 Dec 5;82(11):1643-1647. doi: 10.1292/jvms.20-0306. Epub 2020 Sep 18.
This study investigated consecutive fluctuations in serum activities of bone-specific alkaline phosphatase (ALP) isoenzyme 3 (ALP3) in 11 clinically healthy Holstein heifers during the first 18 months of life. ALP3 activities at the first sampling time point after weaning (3 months) were significantly lower than those at multiple time points during the pre-weaning period. Those activities increased from a minimum at 3 months to a peak at 6 months during the post-weaning period. In the anthropometric data, daily body weight and wither height gains appeared to be below the public data at 4 months and 4-5 months, respectively. The data suggested that serum ALP3 activity can be used to monitor skeletal growth of heifers at weaning.
本研究调查了11头临床健康的荷斯坦小母牛在出生后18个月内血清骨特异性碱性磷酸酶（ALP）同工酶3（ALP3）活性的连续波动情况。断奶后（3个月）首个采样时间点的ALP3活性显著低于断奶前多个时间点的活性。在断奶后时期，这些活性从3个月时的最低值增加到6个月时的峰值。在人体测量数据中，日体重增加和鬐甲高度增加在4个月和4至5个月时似乎分别低于公开数据。数据表明，血清ALP3活性可用于监测小母牛断奶时的骨骼生长情况。
