Koudstaal P J
Tijdschr Gerontol Geriatr. 1987 Apr;18(2):65-8.
To assess the possibilities of treatment of acute cerebral infarction the results of clinical trials, performed during the past 30 years, are reviewed. Only a few studies fulfil basic requirements for a clinical trial, such as sufficient sample size. A therapeutic effect could not be proven in any of these studies. On the other hand, because of the small number of patients, therapeutic inactivity equally could not be established. In conclusion, present knowledge does not justify any treatment for acute cerebral infarction. In the near future well organized clinical trials will have to provide more definite results.
为评估急性脑梗死的治疗可能性，回顾了过去30年进行的临床试验结果。只有少数研究满足临床试验的基本要求，如足够的样本量。在这些研究中均未证实有治疗效果。另一方面，由于患者数量少，同样无法确定治疗无效。总之，目前的知识无法证明对急性脑梗死进行任何治疗是合理的。在不久的将来，精心组织的临床试验必须提供更明确的结果。
