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与慢性感染相关的结直肠癌

Colorectal Cancer Related to Chronic Infection.

作者信息

Sava M, Huynh T, Frugoli A, Kong L, Salehpour M, Barrows B

机构信息

Western University of Health Sciences, Ventura, CA, USA.

Community Memorial Health Systems, Graduate Medical Education, Ventura, CA, USA.

出版信息

Case Rep Gastrointest Med. 2020 Sep 7;2020:8886460. doi: 10.1155/2020/8886460. eCollection 2020.

DOI:10.1155/2020/8886460
PMID:32963848
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7492975/
Abstract

The majority of individuals with () colitis are clinically asymptomatic. Symptomatic individuals may complain of nonspecific gastrointestinal symptoms, such as abdominal pain, intermittent or persistent diarrhea, nausea, or loss of appetite. In addition, skin manifestations such as recurrent urticaria can occur. If infection is not diagnosed and left untreated, it can lead to chronic inflammation of the gastrointestinal tract. It is well documented that chronic colitis such as inflammatory bowel disease can predispose individuals to colorectal cancer. Additionally, there is evidence of chronic parasitic infections inducing the development of cancers in other organs within the gastrointestinal tract. In this case vignette, we describe a case of chronic infection in a Peruvian woman presenting with colorectal cancer.

摘要

大多数患有()结肠炎的个体临床上无症状。有症状的个体可能会抱怨非特异性胃肠道症状,如腹痛、间歇性或持续性腹泻、恶心或食欲不振。此外,还可能出现复发性荨麻疹等皮肤表现。如果感染未被诊断和治疗,可能会导致胃肠道慢性炎症。有充分的文献记载,如炎症性肠病等慢性结肠炎会使个体易患结直肠癌。此外,有证据表明慢性寄生虫感染会诱发胃肠道其他器官的癌症。在本病例中,我们描述了一名患有结直肠癌的秘鲁女性的慢性感染病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2728/7492975/42f21dbe4fbc/CRIGM2020-8886460.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2728/7492975/454047498eff/CRIGM2020-8886460.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2728/7492975/d22dcf1bfff9/CRIGM2020-8886460.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2728/7492975/9ba75729d814/CRIGM2020-8886460.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2728/7492975/42f21dbe4fbc/CRIGM2020-8886460.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2728/7492975/454047498eff/CRIGM2020-8886460.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2728/7492975/d22dcf1bfff9/CRIGM2020-8886460.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2728/7492975/9ba75729d814/CRIGM2020-8886460.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2728/7492975/42f21dbe4fbc/CRIGM2020-8886460.004.jpg

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本文引用的文献

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Morbidity Associated with Chronic Infection: A Systematic Review and Meta-Analysis.慢性感染相关发病情况:系统评价与荟萃分析。
Am J Trop Med Hyg. 2019 Jun;100(6):1305-1311. doi: 10.4269/ajtmh.18-0895.
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Parasites as negative regulators of cancer.寄生虫作为癌症的负调控因子。
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Pearls collections: What we can learn about infectious disease and cancer.珍珠集:我们能从传染病和癌症中学到什么。
Anisakis extracellular vesicles elicit immunomodulatory and potentially tumorigenic outcomes on human intestinal organoids.
异形钩体外囊泡可引起人类肠道类器官的免疫调节和潜在致瘤作用。
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An Unusual Case of Lethal -Associated Chronic Fulminant Colitis in an Immunocompetent Patient.一例免疫功能正常患者发生的与致死相关的慢性暴发性结肠炎罕见病例。
Case Rep Infect Dis. 2024 Jun 27;2024:4223529. doi: 10.1155/2024/4223529. eCollection 2024.
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Bacterial and Parasitic Pathogens as Risk Factors for Cancers in the Gastrointestinal Tract: A Review of Current Epidemiological Knowledge.胃肠道癌症危险因素之细菌和寄生虫病原体:当前流行病学知识综述
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Relationship Among Strongyloides stercoralis Infection, Human T-Cell Lymphotropic Virus Type 1 Infection, and Cancer: A 24-Year Cohort Inpatient Study in Okinawa, Japan.粪类圆线虫感染、人类嗜T淋巴细胞病毒1型感染与癌症之间的关系:日本冲绳一项为期24年的队列住院患者研究。
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