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1995 - 2017年斐济、密克罗尼西亚联邦、巴布亚新几内亚和萨摩亚女性梅毒、淋病和衣原体感染率:Spectrum - STI模型估计值

Prevalence of syphilis, gonorrhoea and chlamydia in women in Fiji, the Federated States of Micronesia, Papua New Guinea and Samoa, 1995-2017: Spectrum-STI 
model estimates.

作者信息

Nishijima Takeshi, Nand Devina, David Nefertti, Bauri Mathias, Carney Robert, Htin Khin Cho Win, Shwe Ye Yu, Gurung Anup, Mahiane Guy, Ishikawa Naoko, Taylor Melanie M, Korenromp Eline L

机构信息

WHO Regional Office for the Western Pacific, Manila, Philippines.

Ministry of Health and Medical Services, Fiji.

出版信息

Western Pac Surveill Response J. 2020 Mar 31;11(1):29-40. doi: 10.5365/wpsar.2019.10.2.003. eCollection 2020 Jan-Mar.

Abstract

OBJECTIVE

To estimate prevalence levels of and time trends for active syphilis, gonorrhoea and chlamydia in women aged 15-49 years in four countries in the Pacific (Fiji, the Federated States of Micronesia [FSM], Papua New Guinea [PNG] and Samoa) to inform surveillance and control strategies for sexually transmitted infections (STIs).

METHODS

The Spectrum-STI model was fitted to data from prevalence surveys and screenings of adult female populations collected during 1995-2017 and adjusted for diagnostic test performance and to account for undersampled high-risk populations. For chlamydia and gonorrhoea, data were further adjusted for age and differences between urban and rural areas.

RESULTS

Prevalence levels were estimated as a percentage (95% confidence interval). In 2017, active syphilis prevalence was estimated in Fiji at 3.89% (2.82 to 5.06), in FSM at 1.48% (0.93 to 2.16), in PNG at 3.91% (1.67 to 7.24) and in Samoa at 0.16% (0.07 to 0.37). For gonorrhoea, the prevalence in Fiji was 1.63% (0.50 to 3.87); in FSM it was 1.59% (0.49 to 3.58); in PNG it was 11.0% (7.25 to 16.1); and in Samoa it was 1.61% (1.17 to 2.19). The prevalence of chlamydia in Fiji was 24.1% (16.5 to 32.7); in FSM it was 23.9% (18.5 to 30.6); in PNG it was 14.8% (7.39 to 24.7); and in Samoa it was 30.6% (26.8 to 35.0). For each specific disease within each country, the 95% confidence intervals overlapped for 2000 and 2017, although in PNG the 2017 estimates for all three STIs were below the 2000 estimates. These patterns were robust in the sensitivity analyses.

DISCUSSION

This study demonstrated a persistently high prevalence of three major bacterial STIs across four countries in WHO's Western Pacific Region during nearly two decades. Further strengthening of strategies to control and prevent STIs is warranted.

摘要

目的

评估太平洋地区四个国家(斐济、密克罗尼西亚联邦、巴布亚新几内亚和萨摩亚)15 - 49岁女性中活动性梅毒、淋病和衣原体感染的流行水平及时间趋势,为性传播感染(STIs)的监测和控制策略提供依据。

方法

将Spectrum - STI模型应用于1995 - 2017年期间收集的成年女性人群患病率调查和筛查数据,并根据诊断测试性能进行调整,同时考虑高危人群抽样不足的情况。对于衣原体和淋病,数据进一步按年龄以及城乡差异进行调整。

结果

患病率以百分比(95%置信区间)估计。2017年,斐济活动性梅毒患病率估计为3.89%(2.82至5.06),密克罗尼西亚联邦为1.48%(0.93至2.16),巴布亚新几内亚为3.91%(1.67至7.24),萨摩亚为0.16%(0.07至0.37)。淋病患病率方面,斐济为1.63%(0.50至3.87);密克罗尼西亚联邦为1.59%(0.49至3.58);巴布亚新几内亚为11.0%(7.25至16.1);萨摩亚为1.61%(1.17至2.19)。衣原体感染患病率在斐济为24.1%(16.5至32.7);密克罗尼西亚联邦为23.9%(18.5至30.6);巴布亚新几内亚为14.8%(7.39至24.7);萨摩亚为30.6%(26.8至35.0)。对于每个国家的每种特定疾病,2000年和2017年的95%置信区间有重叠,尽管在巴布亚新几内亚,2017年所有三种性传播感染的估计值均低于2000年的估计值。这些模式在敏感性分析中是稳健的。

讨论

本研究表明,在近二十年中,世卫组织西太平洋区域四个国家的三种主要细菌性性传播感染患病率持续居高不下。有必要进一步加强性传播感染的控制和预防策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7a9/7485516/e574885bdcdc/WPSAR.2020.11.1-033-F1.jpg

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