铜催化末端炔烃的马氏硅氢化反应
Copper-Catalyzed -Markovnikov Hydrosilylation of Terminal Alkynes.
作者信息
Wang Zi-Lu, Zhang Feng-Lian, Xu Jian-Lin, Shan Cui-Cui, Zhao Meng, Xu Yun-He
机构信息
Department of Chemistry and Hefei National Laboratory for Physical Sciences at Microscale, University of Science and Technology of China, Hefei 230026, China.
State Key Laboratory and Institute of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, China.
出版信息
Org Lett. 2020 Oct 2;22(19):7735-7742. doi: 10.1021/acs.orglett.0c02952. Epub 2020 Sep 23.
A copper-catalyzed -Markovnikov hydrosilylation of alkynes with PhSiH was reported. This reaction represents a notable and efficient example on copper-catalyzed hydrosilylatioin of alkynes, which shows excellent recognition between the terminal and internal triple bonds. Various (hetero)aromatic and aliphatic substituted terminal alkynes underwent this reaction to afford the ()-vinylsilanes in high yields and with excellent regioselectivity.
据报道，实现了铜催化的炔烃与苯基硅烷的反马氏氢硅化反应。该反应是铜催化炔烃氢硅化反应中一个显著且高效的例子，它对末端和内炔三键表现出出色的区分能力。各种（杂）芳基和脂肪族取代的末端炔烃都能发生此反应，以高收率和优异的区域选择性得到（）-乙烯基硅烷。
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