Lader M
Am J Med. 1987 May 22;82(5A):20-6. doi: 10.1016/0002-9343(87)90199-9.
Benzodiazepine anxiolytics are known to pose risks associated with drug dependence, abuse, and withdrawal symptoms. Recently, a new antianxiety agent, buspirone, was introduced in the United States. Buspirone appears to lack abuse liability and does not lead to drug dependence or withdrawal symptoms. This article reviews the results of animal and clinical studies in which the potential for buspirone dependence or abuse and the effects of its withdrawal were assessed.
苯二氮䓬类抗焦虑药已知存在与药物依赖、滥用及戒断症状相关的风险。最近，一种新型抗焦虑药丁螺环酮在美国上市。丁螺环酮似乎不存在滥用倾向，也不会导致药物依赖或戒断症状。本文综述了评估丁螺环酮依赖或滥用可能性及其戒断效应的动物和临床研究结果。
