Research Associate, Centre for Health Services Studies, University of Kent, Canterbury, UK.
Sessional GP & Sessional General Practitioner and Honorary Research Fellow, Centre for Health Studies, University of Kent, Canterbury, UK.
Prim Health Care Res Dev. 2020 Sep 24;21:e36. doi: 10.1017/S1463423620000365.
The review aimed to identify factors influencing opioid prescribing as regular pain-management medication for older people.
Chronic pain occurs in 45%-85% of older people, but appears to be under-recognised and under-treated. However, strong opiate prescribing is more prevalent in older people, increasing at the fastest rate in this age group.
This review included all study types, published 1990-2017, which focused on opioid prescribing for pain management among older adults. Arksey and O'Malley's framework was used to scope the literature. PubMed, EBSCO Host, the UK Drug Database, and Google Scholar were searched. Data extraction, carried out by two researchers, included factors explaining opioid prescribing patterns and prescribing trends.
A total of 613 papers were identified and 53 were included in the final review consisting of 35 research papers, 10 opinion pieces and 8 grey literature sources. Factors associated with prescribing patterns were categorised according to whether they were patient-related, prescriber-driven, or system-driven. Patient factors included age, gender, race, and cognition; prescriber factors included attitudes towards opioids and judgements about 'normal' pain; and policy/system factors related to the changing policy landscape over the last three decades, particularly in the USA.
A large number of context-dependent factors appeared to influence opioid prescribing for chronic pain management in older adults, but the findings were inconsistent. There is a gap in the literature relating to the UK healthcare system; the prescriber and the patient perspective; and within the context of multi-morbidity and treatment burden.
本综述旨在确定影响将阿片类药物作为老年人常规疼痛管理药物的处方的因素。
慢性疼痛在 45%-85%的老年人中发生,但似乎未被充分认识和治疗。然而,在老年人中,强阿片类药物的处方更为普遍,在这个年龄段的增长速度最快。
本综述包括所有研究类型,发表时间为 1990 年至 2017 年,重点关注老年人疼痛管理中的阿片类药物处方。阿斯基和奥马利的框架被用于确定文献范围。使用 PubMed、EBSCO 主机、英国药物数据库和谷歌学术进行检索。由两名研究人员进行数据提取,包括解释阿片类药物处方模式和处方趋势的因素。
共确定了 613 篇论文,最终综述包括 53 篇论文,其中包括 35 篇研究论文、10 篇观点文章和 8 篇灰色文献来源。根据与处方模式相关的因素是否与患者相关、与处方者相关或与系统相关进行分类。患者因素包括年龄、性别、种族和认知;处方者因素包括对阿片类药物的态度和对“正常”疼痛的判断;以及与过去三十年政策变化相关的政策/系统因素,特别是在美国。
大量与背景相关的因素似乎影响了老年人慢性疼痛管理中阿片类药物的处方,但研究结果不一致。文献中存在与英国医疗保健系统、处方者和患者视角以及多疾病和治疗负担背景相关的空白。