Jalil Palwasha, Masood Sadia, Fatima Saira
Dermatology, Aga Khan University Hospital, Karachi, PAK.
Histopathology, The Aga Khan University, Karachi, PAK.
Cureus. 2020 Aug 20;12(8):e9906. doi: 10.7759/cureus.9906.
Erythema annulare centrifugum (EAC) is an unusual skin condition appearing as recurrent erythematous annular eruptions associated with autoimmune disorders, infections, and various neoplastic conditions. We present a very rarely reported association of EAC with Hashimoto thyroiditis (HT) in a young male. A 26-year-old male recently diagnosed as case of HT presented in the dermatology clinic with nine-month history of non-itchy persistent annular lesions on the body. The morphology and biopsy of lesions confirmed the diagnosis of EAC. HT is a part of the spectrum of autoimmune thyroid diseases with its own specific cutaneous manifestations. Our case also depicts the impact of antigen-antibody related immunological reaction, which might be involved in the development of both HT and EAC, and it could be the stages of the same pathological condition of two different clinical presentations.
离心性环状红斑（EAC）是一种罕见的皮肤疾病，表现为与自身免疫性疾病、感染及各种肿瘤性疾病相关的复发性红斑环状皮疹。我们报告了一例年轻男性中EAC与桥本甲状腺炎（HT）的罕见关联。一名最近被诊断为HT的26岁男性到皮肤科门诊就诊，其身体上有持续9个月的非瘙痒性持久性环状皮损。皮损的形态和活检确诊为EAC。HT是自身免疫性甲状腺疾病谱的一部分，有其自身特定的皮肤表现。我们的病例还描述了抗原 - 抗体相关免疫反应的影响，这可能参与了HT和EAC的发生发展，并且可能是同一病理状态的两个不同临床表现阶段。
