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美国国立卫生研究院资助的医学物理研究的领域分类与分析。

Domain classification and analysis of national institutes of health-funded medical physics research.

作者信息

Scarpelli Matthew, Whelan Brendan, Farahani Keyvan

机构信息

Department of Neuroimaging, Barrow Neurological Institute, Phoenix, AZ, 85012, USA.

Image X institute, University of Sydney, Eveleigh, NSW, 2015, Australia.

出版信息

Med Phys. 2021 Feb;48(2):605-614. doi: 10.1002/mp.14469. Epub 2021 Jan 7.

Abstract

PURPOSE

The American Association of Physicists in Medicine (AAPM) previously developed a research database consisting of the National Institutes of Health (NIH) grants that were awarded to its members. The purpose of this report is to classify these NIH grants into various medical physics subdisciplines and analyze the scope of AAPM member research.

METHODS

For this report, an algorithm classified grant topics into medical physics research subdisciplines (grants from 2002 to 2019 were analyzed). This algorithm utilized a search for common words and phrases within grant titles, keywords, abstracts, and activity codes to perform the classification. AAPM member grants were compared with non-AAPM member grants in various relevant subcategories to assess what percentage of these grants was held by AAPM members.

RESULTS

The percentage of AAPM member grants that included words relating to both imaging and therapy (image-guided therapy grants) increased from 13% (27/207) in 2002 to 27% (79/293) in 2019. The percentage of AAPM member grants utilizing words relating to artificial intelligence increased from 8% in 2002 to 20% in 2019. From 2002 to 2019, AAPM member grants referenced cancer more than all other diseases combined. The majority of AAPM member grants included words relating to clinical research (81% of grants in 2002 and 99% in 2019). When comparing AAPM member with non-AAPM member grants it was found that in 2019 AAPM members held a substantial fraction of all NIH grants that referenced stereotactic radiation therapies (41%), radionuclide therapies (10%), brachytherapies (35%), intensity-modulated radiation therapies (45%), and external beam particle therapies (55%). From 2002 to 2019, the percentage of AAPM membership holding NIH grants decreased for males (3.2% down to 2.3%) and increased for females (0.8% up to 1.3%) CONCLUSIONS: The majority of grants awarded to AAPM members focus on clinical research, which underlies the translational aspect of medical physics and suggests medical physicists are uniquely positioned to help translate new technologies such as artificial intelligence into the clinic. Since 2002, NIH grants awarded to AAPM members have increasingly referenced some form of image-guided therapy, suggesting opportunities for continued innovation of imaging technologies. A substantial fraction of all radiotherapy-related research grants were awarded to AAPM members, emphasizing the important role physicists have in developing radiotherapy-related treatments.

摘要

目的

美国医学物理学家协会(AAPM)此前开发了一个研究数据库,该数据库由授予其成员的美国国立卫生研究院(NIH)资助项目组成。本报告的目的是将这些NIH资助项目分类到不同的医学物理子学科中,并分析AAPM成员的研究范围。

方法

在本报告中,一种算法将资助项目主题分类到医学物理研究子学科中(分析了2002年至2019年的资助项目)。该算法通过在资助项目标题、关键词、摘要和活动代码中搜索常见单词和短语来进行分类。将AAPM成员的资助项目与各个相关子类别中的非AAPM成员资助项目进行比较,以评估这些资助项目中AAPM成员所占的百分比。

结果

包含与成像和治疗相关词汇(图像引导治疗资助项目)的AAPM成员资助项目的百分比从2002年的13%(27/207)增加到2019年的27%(79/293)。使用与人工智能相关词汇的AAPM成员资助项目的百分比从2002年的8%增加到2019年的20%。从2002年到2019年,AAPM成员资助项目提及癌症的次数超过了所有其他疾病提及次数的总和。大多数AAPM成员资助项目包含与临床研究相关的词汇(2002年为81%的资助项目,2019年为99%)。在比较AAPM成员与非AAPM成员的资助项目时发现,2019年,AAPM成员持有所有提及立体定向放射治疗(41%)、放射性核素治疗(10%)、近距离治疗(35%)、调强放射治疗(45%)和外照射粒子治疗(55%)的NIH资助项目的很大一部分。从2002年到2019年,持有NIH资助项目的AAPM成员比例男性有所下降(从3.2%降至2.3%),女性有所上升(从0.8%升至1.3%)。结论:授予AAPM成员的大多数资助项目集中在临床研究上,这构成了医学物理转化方面的基础,并表明医学物理学家处于独特的地位,能够帮助将人工智能等新技术转化到临床应用中。自2002年以来,授予AAPM成员的NIH资助项目越来越多地提及某种形式的图像引导治疗,这表明成像技术有持续创新的机会。所有与放射治疗相关的研究资助项目中有很大一部分授予了AAPM成员,这突出了物理学家在开发放射治疗相关治疗方法中所起的重要作用。

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