黄热病监测挑战：对一只非本地狨猴病例的调查。

Yellow fever surveillance challenge: Investigation of a marmoset non-autochthonous case.

机构信息

Centro de Patologia, Instituto Adolfo Lutz, São Paulo, Brasil; Laboratório de Patologia Comparada de Animais Selvagens, Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo, São Paulo, Brasil.

Centro de Patologia, Instituto Adolfo Lutz, São Paulo, Brasil.

出版信息

Acta Trop. 2020 Dec;212:105702. doi: 10.1016/j.actatropica.2020.105702. Epub 2020 Sep 21.

DOI:10.1016/j.actatropica.2020.105702

PMID:32971069

Abstract

Yellow fever (YF) surveillance in Brazil is focused mainly on the detection of epizootic events regarding New World non-human primates (NWNHP). We present a challenging case of a Callitrichidae (Callithrix spp) kept as a domiciliated pet that lived in the urban area of São Paulo municipality and was positive to YF virus by RT-qPCR and immunohistochemistry. After investigation, it was the first occurrence of non-autochthonous YF case of NWNHP described, with probable place of infection in the North shore of São Paulo state. This case illustrates the importance of coordinated laboratorial and field actions, and risks posed by transit of wildlife.

摘要

巴西的黄热病（YF）监测主要集中在检测新域非人类灵长类动物（NWNHP）的流行事件上。我们报告了一个具有挑战性的案例，一只饲养的卷尾猴科（Callitrichidae）动物（Callithrix 属）作为宠物生活在圣保罗市的城市地区，通过 RT-qPCR 和免疫组织化学检测呈黄热病毒阳性。经过调查，这是首例描述的非本地 NWNHP 黄热病病例，感染地可能在圣保罗州北岸。该病例说明了协调实验室和实地行动的重要性，以及野生动物过境带来的风险。