新型产气克雷伯菌R质粒介导的β-内酰胺酶
Novel R-plasmid-mediated beta-lactamase from Klebsiella aerogenes.
作者信息
Petrocheilou V, Sykes R B, Richmond M H
出版信息
Antimicrob Agents Chemother. 1977 Jul;12(1):126-8. doi: 10.1128/AAC.12.1.126.
Abstract
A novel beta-lactamase with a broad spectrum of activity against penicillins and cephalosporins has been detected in a strain of Klebsiella aerogenes. Its synthesis is mediated by an R-plasmid of molecular weight 64 x 10(6).
摘要
在一株产气克雷伯菌中检测到一种新型β-内酰胺酶，它对青霉素和头孢菌素具有广泛的活性。其合成由分子量为64×10⁶的R质粒介导。
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本文引用的文献
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A comparative study of eight distinct beta-lactamases synthesized by gram-negative bacteria.对革兰氏阴性菌合成的八种不同β-内酰胺酶的比较研究。
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The purification and properties of a penicillinase whose synthesis is mediated by an R-factor in Escherichia coli.一种由大肠杆菌中的R因子介导合成的青霉素酶的纯化及其性质
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The interplay of beta-lactamases and intrinsic factors in the resistance of gram-negative bacteria to penicillins and cephalosporins.β-内酰胺酶与内在因素在革兰氏阴性菌对青霉素和头孢菌素耐药性中的相互作用。
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