Deborah Christensen is an epidemiologist at the Centers for Disease Control and Prevention, Atlanta. Jennifer Zubler is a pediatric consultant at Eagle Global Scientific, San Antonio, TX. Contact author: Deborah Christensen,
Am J Nurs. 2020 Oct;120(10):30-37. doi: 10.1097/01.NAJ.0000718628.09065.1b.
Autism spectrum disorder (ASD) is a condition characterized by impaired social communication as well as restricted and repetitive behaviors. It is considered a neurodevelopmental disorder because it is associated with neurologic changes that may begin in prenatal or early postnatal life, alters the typical pattern of child development, and produces chronic signs and symptoms that usually manifest in early childhood and have potential long-term consequences. In past decades, autism was conceptualized as a strictly defined set of behaviors, usually accompanied by intellectual impairment. Today, it is recognized as a spectrum, ranging from mild to severe, in which behaviors vary substantially and the majority of children who fall on the spectrum have average to above average intellectual ability. Here, the authors discuss the risk factors for ASD, its epidemiology, common concurrent conditions, evaluation, diagnosis, treatments, and outcomes.
自闭症谱系障碍(ASD)是一种以社交沟通障碍以及受限的、重复的行为为特征的疾病。它被认为是一种神经发育障碍,因为它与神经变化有关,这些变化可能发生在产前或产后早期,改变了儿童典型的发育模式,并产生通常在幼儿期表现出来的慢性症状和体征,且可能有长期影响。在过去的几十年中,自闭症被概念化为一组严格定义的行为,通常伴有智力障碍。如今,它被认为是一个谱系,从轻度到重度不等,其中行为差异很大,大多数处于谱系中的儿童具有平均以上的智力能力。在这里,作者讨论了 ASD 的风险因素、流行病学、常见的并发情况、评估、诊断、治疗和结果。